You need to be particularly wary of the harmala metabolic interactions. This can affect efficacy and clearance of your medications.

Carvedilol, for example, is partly metabolised by CYP2D6, so its elimination half-life, and consequently its peak plasma concentration, is likely to become elevated. This does not seem to be optimal; harmalas have a vasodilatory action which may exacerbate the hypotensive effect.

Similar considerations should be applied to the other medications - if there's already a risk of hyperkalemia, raising the concentration of the causative agent would be further cause for concern. I've seen claims that harmalas can deplete magnesium - this action would also be potentially dangerous in combination with elevated potassium.

I'd be interested to know how you came up with this idea. Hearing more about the etiology of your heart problems might be too much of an ask, but it provides context for a possible grounds to use Syrian rue. I'm not convinced of the wisdom of combining it with all the pharmaceutical medications.

All the signs point to it being better for you to lay off the harmalas, unless perhaps you're getting some fairly comprehensive bloodwork done for a scientific study.