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Exp. Report 4-HO-MiPT: beautiful, optimistic, therapeutic, magical

Experience report

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Dose (hemifumarate):
T+00:00 -> 15mg miprocin, rectal
T+01:00 -> 8mg miprocin, rectal
(note: I think my scale may not have been accurate for such low amounts, and it may have been more. I need a better scale)

Timeline summary:
T+00:05 -> First alert (uneasy bodily feeling, strange taste in my tongue)
T+00:15 -> Come-up starts
T+00:35 -> Come-up seems to stop, apparent weak "peak"
T+01:00 -> Booster dose
T+01:1? -> Come-up continues, very fast
T+01:?? -> Very strong peak
T+01:4? -> Plateau starts
T+03:?? -> Comedown starts
T+05:?? -> Most effects almost residual, physical stimulation still significant
T+07:00 -> Stimulation low enough to be willing to lie down and try to sleep
T+08:?? -> Able to fall asleep

Since some time ago, I've been intrigued about miprocin from reading @Varallo's positive reports and opinions on it. I had initially planned to take Aya today, but I'm going through a rough spot, and last time Aya had a destabilizing effect for the following week. So I thought a more light-hearted kind of experience could be more adequate to the situation, and it seemed a good moment to try miprocin, as I may not be in a context where I can try it again in some time.

I think there was some internal conflict between fear and the wish to push myself a bit. I initially planned a modest, introductory dose. But in the end I decided a moderate one, and had a booster in hand just in case.

It went differently from what I'd planned. When applying the first dose, an indeterminate amount came out by accident. Now I think it was just a small drop (and I had diluted it more than necessary just in case this would happen), but I got worried it may be a lot and the trip would be lackluster. The come-up started very soon and evolved fast at first, but then it seemed to come to a standstill (after 20 minutes of come up, and for about half an hour). I thought I was either at the peak or close, so I decided to add the booster dose I had prepared, 8mg. And I thought it may not be enough anymore to do anything else but prolong it. I was at a spot with a lot of muscle twitches and a strange mindspace, but otherwise feeling quite normal, with only minor visual activity. Interestingly, my intestines seemed to be moving a lot, even if I had not taken it orally. But no bloating or discomfort, it was muscular.

I was quite wrong about having reached the peak (now in retrospective it seems obvious), and after some time it increased in intensity again, very fast. I was not worried or scared, but a lot of difficult mental material started coming up in a very "embodied" way, with very strong muscle tension, shaking, and feeling very hot. I entered in some kind of trance/embodied memory/whatever it is, similar to the state I entered with pharmahuasca in log XII (and then later), where I thought I was having a heat stroke. I was "embodying" some painful mental issues, fully immersed in them. All this was so intense it's not easy to remember the specifics, but I was reliving several past scenes at once, while I felt whatever this "overheating" is.

It's interesting that, unlike mushrooms, it didn't become loopy or dark, despite the difficult nature of the experience at this point. There seemed to be an underlying "optimistic force". It also was much less transcendental than pharma/Aya: more than about Life and Mind, it was about my life and my mind. After a while (must have been about T+01:30, I'm unsure when the peak started) I regained some awareness and I actually had a period of intense euphoria. And this happened throughout the plateau: waves of more difficult material (but now less difficult, having had that strong release at the peak) and waves of euphoria and "resolution", not only in feeling but in considering actual, practical solutions, plus feeling the motivation to actually carry them through.

Visually, it was extremely active and gorgeous. It has been my first trip with eyes open in a long time, and I really enjoyed its OEVs. There was a lot of morphing and patterning, e.g. everything turning into fern-like structures, and both fractal and cubist-like patterns. At one point, I got entranced looking at a streetlight through my curtain, and a face of a goddess appeared that "gave me" a suggestion about how to deal with my current situation. The specifics of the suggestion don't fully hold up when examined in a sober state, but the gist of it is exactly right (basically, I need some psychological help to deal with the life events I'm going through) and I'm already in motion to implement it.

Physically, it was very strongly stimulating. I had planned to just lie down, but I regularly needed to move, stretch, even dance. My shoulder and neck muscles were very very tense, and I had some jaw clenching too. This is maybe the aspect I liked the least. I already have a lot of muscle tension with psychedelics (probably) related to psychosomatic stuff, and the stimulation increased it to a very uncomfortable point. Although it's hard to know to what percentage it was the substance and what percentage it was me: it was more physically stimulating than 25mg 2C-B, and I doubt that's the case pharmacologically. This stimulation may prove to be a positive at lower doses, it seems ideal for hiking. At this dose, I had significant stimulation (with mild visual activity) until T+08:00, when I could finally fall asleep. I'm still feeling some very mild stimulation now, at T+14:00.

It has been one of my most significant trips in a very long time. I really appreciate, for my current situation, that it was less "cosmic" than other substances like DMT, and less loopy than mushrooms (although I haven't had mushrooms in a long time), coupled with a kind of optimistic force underlying even the difficult moments. The mentally stimulating, kind of entactogenic push has been really helpful too, to not leave the realizations in realizations only, but actually make the changes I need to (in this case, looking for help).

A minor negative point was that the headspace often felt not very clear, kind of "stoning" as others report. This is in contrast with the feeling of extreme clear mindedness (up to the point of delusions of sobriety) I get with DMT. But it may have been helpful in this instance, it's hard to know.

All in all, this was profound, wonderful, enjoyable (even if pretty hard), and hopefully transformative. So thank you @Varallo for putting it in my radar with your reports here <3

I think this is a very interesting and valuable substance, not some kind of second-rate "mushroom substitute", and will explore it more at some point in the future.
 
I do not think you need a better scale, you need to dose volumetrically.

Thanks for sharing the report. I have observed stimulation with this compound as well as with 4-aco-MET recently as well. Good to hear you have gotten value out of the experience.
 
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you need to dose volumetrically
I agree, still a better scale won't hurt. In this specific situation volumetric dosing wasn't an option as I don't have anywhere to store the solution, but I will dissolve it soon.

The physical stimulation really surprised me, it being stronger than 25mg 2C-B was unexpected. It also had a very pro-social feeling to it, which is not something I tend to experience on tryptamines.
 
I would suggest dissolving in 40% spirits, about 50-70mg in a 30ml-50ml brown glass vial. The vial can be stored at the back of the fridge where the temp. is about 0 degree celsius. It should store quite well.


The comparison of stimulation compared to 2C-B is maybe counter-intuitive, however it can indeed happen. Just because something is an analog of something else does not necesariliy mean certain things that we like to assume. Also the gastrointestinal discomfort is not surpising even though you dosed rectaly. Therefore I like to test new compounds in very low doses to see how I react. Having experienced quite uncomfortable body tension and elevated heart rate with 4-aco-MET on a 5mg dose in a sedentary context, I don't see myself using this compound at higher dosages. I lack the appetite for the potentially strong side effects with lack of proper psychedelic depth. A bit higher dose (not more than a few mg) might be approprite for hiking and running around though. This test I did is showing me that psilohuasca is for myself clearly a better option in terms of quality effects vs. side effects.

In general though it seems some of us are more prone to this type of side effects. What I find interesting is the psychosomatic connection you're mentioning. I feel exploration of this with psychedelics can show me (us) some unexpected truths about my emotions and trauma.
 
I would suggest dissolving in 40% spirits
That's what I usually do (vodka), but in this case I want to keep it possible to use the rectal ROA. So I'm considering bacteriostatic water.

Also the gastrointestinal discomfort is not surpising even though you dosed rectaly
I agree, particularly given it wasn't even discomfort, it was closer to muscle spasms plus gut motility, and those were happening elsewhere as well. It only happened during the come-up.

I lack the appetite for the potentially strong side effects with lack of proper psychedelic depth
I wouldn't say it lacked depth, although it did lack features like strong ego dissolution. This is about 4-HO-MiPT, I'm not sure how it compares in depth with 4-AcO-MET/4-HO-MET, as I haven't tried the latter. Reports I've read seem to point towards miprocin tending to have more depth than metocin, but also significantly more physical stimulation.

In my case, I'd say pharma/Aya are more beneficial to me in general, but as can be seen in this case I got a higher benefit from this experience than from my average pharma/Aya one. However, the substance is only one factor of what makes a experience relevant or beneficial.

In general though it seems some of us are more prone to this type of side effects. What I find interesting is the psychosomatic connection you're mentioning. I feel exploration of this with psychedelics can show me (us) some unexpected truths about my emotions and trauma.
Yes, I completely agree. Not only have I experienced this type of "overheating" and tension with pharma/Aya, but also with LSD and mushrooms, many years ago. And I do instantly with vaped DMT, that's why I'm hesitant to go for larger doses. It's indeed very interesting.
 
I wouldn't say it lacked depth, although it did lack features like strong ego dissolution. This is about 4-HO-MiPT, I'm not sure how it compares in depth with 4-AcO-MET/4-HO-MET, as I haven't tried the latter. Reports I've read seem to point towards miprocin tending to have more depth than metocin, but also significantly more physical stimulation.
I've just used the 4-aco-MET as an example of the careful substance testing to see the reaction. Otherwise I'm quite certain 4-ho-MiPT has more depth to it. Not sure about the physical stimulation though. It probably varies from person to person.
 
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