DMT is active sublingually, but only at gigantic doses, like 100 mg and up, while 5-MeO-DMT is active at doses as little as 1 mg. So because 5-MeO-DMT is so potent sublingually, you can take a very large 5-MeO-DMT dose with DMT in the mix and the DMT dose will be too small to do anything at all.