Asthma and mushies or sclerotia

[Phlux-]

recently a friend had a asthma attack while purging on 27.5g sclerotia - it was intense and he was certain he was going to die.

alot of fungus can induce phlegm - combined with asthma this can be potentially dangerous - so my advice is always to have an asthma inhaler with you if you have asthma and intend to trip.

 

[biopsylo]

that sounds scary, indeed.

interesting, because some mushrooms are quite beneficial to the lungs and airways (like reshi ). they actually help clear passages.

i have not been diagnosed with asthma, but under certain conditions, breathing becomes more difficult, and tincture with reshi, and other herbs -thyme, lobelia, etc really helps out. i try to aspirate the tincture by taking deep breaths while it is in my mouth.

 

[Aetherius Rimor]

Remember asthma is an allergic response typically, and your friend might just be allergic to mushrooms.

My asthma has never flaired up from their use, then again I've never done more than 6 (dried) grams.

 

[corpus callosum]

Remember asthma is an allergic response typically, and your friend might just be allergic to mushrooms.

quote]

^^Pertinent observation.Another possibility for the asthma attack which occurs whilst purging is aspiration of small amounts of vomitus entering the large airways causing bronchospasm.

 

[Phlux-]

iv had this suffocation while jackpotting before - it wasnt fun.
my friend is not allergic - it was just all the phlegm he had i spoze.
best to be prepared in anycase


corpus - can this lead to asphyxiation and potentially expiration of the fungal consumer ? and would common resuscitation work if that ever happened ? (best to know these things) - (it seems everyone learned cpr from baywatch haha)

 

[Aetherius Rimor]

Ahhh, I see your point now.

The fungus generates a lot of phlegm which exacerbates existing asthma. Good point.

 

[Aetherius Rimor]

corpus - can this lead to asphyxiation and potentially expiration of the fungal consumer ? and would common resuscitation work if that ever happened ? (best to know these things) - (it seems everyone learned cpr from baywatch haha)

If it's a combination of phlegm and bronchoconstriction, common resuscitation would be very difficult I think without a Beta2 Adrenergic agonist.

You can die from asthma alone, without an unusual excess of phlegm.

Though I don't recommend this as a first response if unnecessary, in a true emergency, most amphetamines and some phenylethylamines will have Beta2 adrenergic agonistic effects and relieve symptoms of an asthma attack even if not normally prescribed/used for asthma.

MDMA, Adderall, Vyvanse, Desoxyn, Epinephrine, etc. Ephedrine tablets are the OTC asthma treatment in America (preferred the epinephrine inhalers before they were banned) and Albuterol/Salbutamol is the prescription only treatment.

 

[corpus callosum]

The fungus generates a lot of phlegm which exacerbates existing asthma.

Mucus hypersecretion in asthma: causes and effects

Airway mucus plugging has long been recognized as a principal cause of death in asthma. However, molecular mechanisms of mucin overproduction and secretion have not been understood until recently. These mechanisms are reviewed together with ongoing investigations ...

www.ncbi.nlm.nih.gov

^^Heres a good article on the pathophysiology of mucus hypersecretion in the respiratory tract.It mentions fungi briefly but the implication is that their mucogenic effect is related to exposure of the respiratory epithelium to inhaled fungal constituents.Im not aware that oral ingestion of psilocybes does this in all who take them; amanitas, IIRC, are more able to induce mucus production, hypersalivation and increased lacrimation.

Aspiration of vomit can certainly induce acute asthma attacks due to irritation of the airways causing the bronchoconstriction which is a haalmark of the asthmatic process.A fair indicator of how severely any one asthmatic would suffer as a result of aspiration can be gleaned by a history of labile or severe asthma before, a requirement for multiple agents (B2 agonists, anticholinergics, inhaled steroids, theophyllines, oral steroids, immunosuppressants, immunomodulators) to keep their asthma 'controlled' (the greater the number of these used often equals more severe attacks), smoking, inadvertent use of certain meds (eg NSAIDs) etc.

In severe asthma attacks giving mouth to mouth would be inadequate to overcome the airways resistance and invariably hospital input will be required where supplemental oxygen (usually by mask or nasal cannulae), nebulised bronchodilators , steroids (oral if less severe, IV if life-threatening) will be given.Salbutamol can also be given IV if necessary , and so can theophyllines and Ive also seen nebulised epinephrine used when respiratory arrest appears imminent.Very occasionally these treatments dont work as hoped in which case mechanical ventilation and a spell in ICU with continuation of the bronchodilator and steroid therapy IV is the last hope for resolution.

Asthma attacks do unfortunately continue to kill some individuals.The severity of the attack governs which ROA of the treatment meds is the most appropriate in any one case;if the attack is of moderate severity (or worse) then oral bronchodilators (including amphetamine-related compounds) would be wholly inadequate and too slow in effect to be of use.The physiological sympathetic-mediated stress of a severe attack would mean the diversion of blood flow away from the gut would retard absorption of meds across the gut significantly.

 

[Aetherius Rimor]

Good to see a response from someone more knowledgeable than myself.

I never let my asthma get that far. The moment I start noticing symptoms of hypoxia, I'm doing everything I can to obtain something that will treat it.

Never passed out from it before, but gotten close.