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Could DMT be neurotoxic?

Migrated topic.
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DubRules

Rising Star
I have been smoking DMT for a while now.
I use it heavily and with no real purpose.
Doses are never below 50mg, and I often redose repeatedly up to ~100mg.

Within the last two months, my DMT trips have drastically changed.
My trips have consisted of what feels like chemically induced death.
Now, I can feel the chemical (not necessarily dmt, just a chemical) surge through my body and head for my brain.
I get this *tack tack tack* sound in my head, my guardian appears and tells me i took too much and this is game over, and then i spend the next ~5 minutes going through what feels like a battle for life.
Then when I "come back", my body feels like it's dying.
Like a fish out of water, I spend the next 10 minutes desperately gasping for air and having what seems to be small convulsions.

When the DMT is coming on, I swear I can feel nerve endings exploding in my brain.
Back in the day, I used to get a feeling like my brain was imploding from all that was going on in it.
This isn't that.
Now, I get the feeling like parts of my brain are systematically shutting down.
If my brain is shutting down, it makes sense that my body would start to follow.

Anyone else experience this "real time" death?
 
there is no evidence of neurotoxicity from dmt..

but regardless, I think the message from your experiences is pretty clear: TAKE A BREAK!

believe me when I say you are not alone in having 'hyperspace' give people a hard time when they use too much of it. Take this break, use this time off for being productive in life, be healthy (and being self critical! question yourself, are you not abusing? psychedelics and abusing dont mix)..... One day it may come the time when you feel the calling again, but while that is not so, then focus on other things in life.. IMO :)
 
/ Tough Love ON

DubRules: "Doctor, it hurts when I do this"

Doctor: "Don't do that"

Seriously; "I use it heavily and with no real purpose." ---> garbage in, garbage out

When you show respect to yourself and to the entheogen, you will receive uncountable blessings.

/ Tough Love OFF

Take a rest buddy, maybe antrocles can handle that energy but he's a fully trained endurance athlete
AND he only uses small doses.

OF
 
There is no evidence at all pointing towards DMT and neurotoxicity..but I think personally you are abusing DMT..

I mean..if its so bad, why are you doing this to yourself? Id take at least 2 weeks away from all psychedelics if I were you..and then maybe brew up a light ayahuasca brew and make peace with the molecule..you could jsut be experiencing too much of the physical effects without the full journey becasue of tolerance...

Caapi might help you get back to normal..but god man take a break first!..
 
DMT is not toxic. There is no evidence that would support that.

DubRules said:
I use it heavily and with no real purpose.
Click to expand...

Then stop. Why the hell would you use DMT if all it did was make you feel like you were dying? Why would you take it if you didn't get a useful spiritual experience from it?

Take a break. Take a close look at yourself and decide why you were using DMT. You were doing it for some reason, even if you weren't sure what it was.
 
I sometimes experience the tack tack tack you talk of,and the nerve endings exploding in the brain is something I can relate to,also the feeling of warm fluid moving in the brain.

I feel these are definitely physical phenomenon,and not just imagined.

They've never really bothered me,but the thought has crossed my mind that something is happening in there physically,and is there a possibility it might not be entirley for the good?

I do use the spice quite regularly and always approach my journeys very seriously,though sometimes when on harmalas I do like to vape extreme doses.

But I always feel fantastic after my journeys,and take comfort in the fact,that much spice has been vaped,and it hasn't to my knowledge
hurt anyone yet,and I've experienced the pineal crackle since the beginning.

Does anyone else feel these effects,it would be interesting to hear what a brain expert made of it.
 
fractal enchantment said:
There is no evidence at all pointing towards DMT and neurotoxicity..but I think personally you are abusing DMT..

I mean..if its so bad, why are you doing this to yourself? Id take at least 2 weeks away from all psychedelics if I were you..and then maybe brew up a light ayahuasca brew and make peace with the molecule..you could jsut be experiencing too much of the physical effects without the full journey becasue of tolerance...

Caapi might help you get back to normal..but god man take a break first!..
Click to expand...

I absoloutely concurr. Because DMT is naturally present in the brain and metabolised extremely quickly, its unlikely that it causes any kind of chemical risk like you are describing. Infact, all of my experience with DMT tells me that it is chemically safe, and that the only risk is of death by astonishment.

Ignoring your body and your discomfort is not wise, ma man. Its trying to tell you something.

Who else here feels that DMT is completely safe? that this man's current state is due to his improper use?
 
Under the wrong conditions, DMT can do some psychological damage. It sounds like you are taking it under the wrong conditions.
 
shoe said:
Who else here feels that DMT is completely safe? that this man's current state is due to his improper use?
Click to expand...

I do, but on a couple of occasions I swear I've carried on pulling from my pipe once the lighters gone out and not realised and got me a headache.

In my last house I burned the carpet a little with a hot bulb... first time I used the bulb method was also the last :)

But yeah... DMT is only as safe as mind it falls onto.
 
Posts like this are quite disturbing in that here we have a person smoking a home refined extract of a plant produced endogenous neurochemical to excess.They complain of feeling "neurotoxic" it seems the first question should be of the purity or impurity as leftover petroleum will cause neurotoxicity especially in the usage outlined. Then there is that this is a plant extract.This can contain oils and many other contaminants that smoking may be harmful or cause discomfort.
There is really no information on the effects of prolonged smoked DMT. Although there is a large body of cultural and scientific backing of the oral use in mixed alkaloid "brews" and insufflated base being beneficial there is no study saying such regarding the vaporized base or mixed alkaloidal smoking blends.While this fellow seems to be going quite overboard in use it should also be a clear warning that the toys we play with are in fact dangerous and the potential for someone to be hurt is only a mistep away.
SB
 
Take some time to cleanse your methods (extraction, administration), cleanse your mind (intention of use, focus), and your body (remain active, avoid sedentary behavior). You'll likely feel much better about the experience after ruling out any of these potential problems. Your assessment of the source of the problem is likely a bit hasty, as there's little to validate the possibility of neuro-toxicity.
 
I agree with everybody here.. u need a long break for urself. Its a chemical and effects brain at last, even if u play chess too much you will confuse and glitch your brain.

Plus to be honest here it sounds to me that you are growing a paranoia of death on DMT trip. So everytime u smoke ur mind gives u the feeling that you expect, panik attacks can be another explanation for such thing... So without being a doctor its hard to understand whats goin on in ur brain dude.

If you listen to me give a long break and observe if you are having a sudden "fear of death" feeling sometimes. without takin any substance in ur daily life which is a symptom for panik attack. So if you are having.. I strongly recommend you to take a break for any substance including weed for at least 4-5 months.. Because it can get very serious if u dont take care of urself.

And if you are asking yes I have experienced the "real time death" as u defined on very high dose LSD.. actually even saw the white light and came back. And its not a gud experience... also had a trip with salvia that i thought i was really dead.. but ur trip sounds a bit more physical than my salvia trip.. but still im sure not chaotic plus physical as my acid overdose trip.

So dude abusing sykedeliks is just abusing urself... as Fractal Enhancement said after few months break just start with a low dose ayahuasca... if its still the same, i advice u to totally quit dmt family of drugs..

And i had a question which seems not much related but, are u using those stupid "legal smokes/highs" kinda stuff ? like spice, smoke, bonzai , pulse etc... ?
 
maybe somethign to do with the SOLVENTS

even though they evaporate.. there is still residue..


try a fasa or fasw with food safe chemicals instead, that way your end product is precipitated from the np solvent (which is better if using limonene or something natural anyway) and then you have less risk of smoking petroleum..


oh and dont use lye, it gets pulled into the solvents.
 
etherealsamba said:
maybe somethign to do with the SOLVENTS

even though they evaporate.. there is still residue..

try a fasa or fasw with food safe chemicals instead, that way your end product is precipitated from the np solvent (which is better if using limonene or something natural anyway) and then you have less risk of smoking petroleum..

oh and dont use lye, it gets pulled into the solvents.
Click to expand...

Your advice isn't all that helpful here, merrily carrying on telling the guy to get a better extract when clearly he needs to work on improving his life, restoring the balance and other psychological issues. They could be very real and possibly dangerous, and you just throw a 'extract with limonene' in there??

@DubRules: when you do return to smoke DMT, make sure that you are using an extract of high purity. I personally think that that should be part of the spiritual persuit of extracting and preparing spice. Good clean spice shows a good clean healthy attitude and lifestyle. - shows that you are prepared to put the work in to refine it. sends a good message to the spirits! :p
 
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