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DMSO & DMT

poweroffire

Rising Star
You can buy a glass vial of DMSO.
This is a great liquid to allow rapid absorption of DMT, bringing instant snowflakes.
Recommended for experienced trippers!
but newbies give it a try!

VERY LITTLE. Do NOT USE ALOT.
Get a 31 gauge needle and tap out 1 tiny tiny tiny drop of dmso liquid into your dmt scoop.
NEVER use more than 2-4, 31 gauge drops per half gram of raw dmt.
You can if you want to, but then if you burn the cartridge if making carts, it will ruin the entire cart and will smell and taste like expired chinese food. thus making it untolerable to inhale or smell.

If using on raw, 2, 31 gauge drops on 1/4 gram of dmt. wallah. dissolves instantly in the dmso, and can be nicely molded to a little gold booger that you will then put in your choice of device, to then smoke your boogers!

Let me know what you guys experience!
I snowflaked for like 6 months daily XD
 
You can buy a glass vial of DMSO.
This is a great liquid to allow rapid absorption of DMT, bringing instant snowflakes.
Recommended for experienced trippers!
but newbies give it a try!

VERY LITTLE. Do NOT USE ALOT.
Get a 31 gauge needle and tap out 1 tiny tiny tiny drop of dmso liquid into your dmt scoop.
NEVER use more than 2-4, 31 gauge drops per half gram of raw dmt.
You can if you want to, but then if you burn the cartridge if making carts, it will ruin the entire cart and will smell and taste like expired chinese food. thus making it untolerable to inhale or smell.

If using on raw, 2, 31 gauge drops on 1/4 gram of dmt. wallah. dissolves instantly in the dmso, and can be nicely molded to a little gold booger that you will then put in your choice of device, to then smoke your boogers!

Let me know what you guys experience!
I snowflaked for like 6 months daily XD
You'll have to explain what you mean by "snowflaked". Not everybody uses this slang. Please check the attitude.

For that matter, your entire post is somewhat unclear - what exactly is the advantage of adding DMSO to the DMT? And what do you mean by "if using raw"?
 
i think he means DMSO/ . is a.. SOLVENT.. that will penatrate the human skin alowing dmt in transdermally...if dmt is mixed with it..?

Im not shure that ....DMSO .... a chemicle that melts into the skin is safe?

i doubt it will work,,,


Dimethyl sulfoxide (DMSO) is an organosulfur compound with the formula (CH3)2SO. This colorless liquid is the sulfoxide most widely used commercially. It is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water. It has a relatively high boiling point. DMSO is metabolised to compounds that leave a garlic-like taste in the mouth after DMSO is absorbed by skin.[5
 
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In the past with tests on this platform whole body parts were covered in DMSO, with DMT, and that did absolutely do NOTHING for DMT effects (except making you smell bad).

So please explain why this should work for you (or anyone else) and give us real evidence for this (thus beyond the 'it really worked, trust me' stuff).

Or maybe you mean with "instant snowflakes" the instant rather not so unlike union smell of DMSO? 🤨


Kind regards,

The Traveler
 
i think he means DMSO/ . is a.. SOLVENT.. that will penatrate the human skin alowing dmt in transdermally...if dmt is mixed with it..?

Im not shure that ....DMSO .... a chemicle that melts into the skin is safe?

i doubt it will work,,,


Dimethyl sulfoxide (DMSO) is an organosulfur compound with the formula (CH3)2SO. This colorless liquid is the sulfoxide most widely used commercially. It is an important polar aprotic solvent that dissolves both polar and nonpolar compounds and is miscible in a wide range of organic solvents as well as water. It has a relatively high boiling point. DMSO is metabolised to compounds that leave a garlic-like taste in the mouth after DMSO is absorbed by skin.[5
DMSO is one of the most safest substances out there. It is commonly used as a cryoprotectant in the preservation of embryos.. that safe. Although also a solvent, it's healing properties have been spoken about with some pretty surprising anecdotes within widely varied ailments. I personally have used it for years for all things muscular, joints, headaches, skin, nervous system and swear by it. Some holistic vets have used it on benign growth on dogs and see them disappear. Race horses can sometimes get rubbed down with it after races to relieve their muscles. It is more than safe, its healing.

Precautions are that they'll draw into the skin whatever's on it.. interesting that the DMT did not absorb enough to make an effect. I suppose, not into the system at a high enough rate.

I came here to see what others had experimented with, as I know the power of DMSO and what it could do to help DMT..
 
What about drinking harmalas before?
Since the DMT will not effectively penetrate the skin, even not with DMSO, you will probably only feel the effects of the harmalas.

If DMT were to penetrate the skin and enter the bloodstream, it would bypass the first-pass metabolism in the liver (which occurs when substances are ingested orally). Instead, it would be subject to metabolism by cytochrome P450 enzymes in the liver after entering systemic circulation, similar to when DMT is administered via smoking, vaping, or injection.

Since no effects were reported with the DMSO containing DMT covering large parts of the skin, we can be pretty sure it did not penetrate the skin.


Kind regards,

The Traveler
 
Since the DMT will not effectively penetrate the skin, even not with DMSO, you will probably only feel the effects of the harmalas.

If DMT were to penetrate the skin and enter the bloodstream, it would bypass the first-pass metabolism in the liver (which occurs when substances are ingested orally). Instead, it would be subject to metabolism by cytochrome P450 enzymes in the liver after entering systemic circulation, similar to when DMT is administered via smoking, vaping, or injection.

Since no effects were reported with the DMSO containing DMT covering large parts of the skin, we can be pretty sure it did not penetrate the skin.


Kind regards,

The Traveler
I agree with trav...

Yes... there is a claim that dmso will cause anything mixed in it to enter through the skin layers..and posibly into the bloodstream..

Could the reason DMT doesnt work transdermally with dmso...be that the dmso some how destroys or alters the dmt?

Also another reason DMSO may not be safe is ...[what if bacteria were on your skin when you aplyed the dmso?

Bacteria ... once in the bloodstream.... cam make you very sick...or worse!....:rolleyes:

you would have to be carfull! and shure!!... of sterolizing ...[cleaning]...your skin first before aplying the DMSO...

read report on DMSO on link below...

also..... there may be an industrial grade ...and a food grade dmso?

I guess one could try ... dmso in a gell or cream form...bought in a health food store?

but i wouldent try the industrial form of DMSO....


click on these 4 words.....[[[DMSO: Uses and Risks]]] and read article....

DMSO: Uses and Risks

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WebMD
https://www.webmd.com › vitamins-and-supplements › d...




May 30, 2023 — The biggest concern of DMSO as a solvent is that when it gets on the skin it will cause anything on the skin to be absorbed. So be sure to ...
Missing: d... Missing:unhealthy ‎|results
 
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Could the reason DMT doesnt work transdermally with dmso...be that the dmso some how destroys or alters the dmt?
This should not happen under physiological conditions - although DMSO can act as a both an oxidising and a reducing agent, this is generally under much harsher conditions.

Also another reason DMSO may not be safe is ...[what if bacteria were on your skin when you aplyed the dmso?
Bacteria are too large for their transdermal absorption, as intact organisms, to be effected by DMSO, The skin has a complete microbiome of its own already - the human body contains and is covered by trillions of bacteria already. If there happened to be a pathological species present whiuch produced a toxin of small enough molecular size, there would be a risk of receiving some kind of transdermal dose of that toxin. Since I'm not a microbial dermatotoxicolgist I can't comment how realistic this scenario might be, nor whether you'd already be in trouble from having the pathological organism on your skin in the first place.
you would have to be carfull! and shure!!... of sterolizing ...[cleaning]...your skin first before aplying the DMSO...
One would also have to ensure that the products on ones skin, either as cosmetic and skin care products or the cleaning/hygiene product itself, won't be a potential source of problems.
but i wouldent try the industrial form of DMSO....
Sensible advice!

One further word of caution is that DMSO may possibly get metabolised into highly toxic dimethyl sulfate and methyl methanesulfonate if it is present in the body in excessively high levels (viz, the case of the toxic woman [Gloria Ramirez]).
 
Hi! I'm new here and just got all my supplies to begin my extraction. I'll be starting tonight and just checking to see if I will find nuggets of info to help. While scrolling through, I noticed "DMSO" and got excited and clicked.

DMSO is known for its ability to penetrate the skin and other biological membranes, making it effective for delivering other substances into the body. It is both water and oil soluble, which allows it to mix with a wide variety of substances. This characteristic makes DMSO useful in various medical and industrial applications.

Applying DMSO on damp skin can indeed expedite its absorption, as water on the skin helps to facilitate its penetration. However, it is crucial to ensure the skin is clean before applying DMSO because any contaminants on the skin can also be absorbed into the bloodstream along with the DMSO.

DMSO has been used to alleviate pain and inflammation related to conditions such as arthritis, strains, sprains, and even for drug extravasation injuries. It also has applications in reducing tissue damage from extravasated chemotherapy drugs and improving conditions like interstitial cystitis.

If you're interested in learning more about DMSO, highly recommend the book "Healing with DMSO" on Amazon.

Thanks for letting me chime in and I cant wait to learn and explore.

I attached the amazon link to the DMSO I recommend and currently have at home! And the book I mentioned!!

 
Hi! I'm new here and just got all my supplies to begin my extraction. I'll be starting tonight and just checking to see if I will find nuggets of info to help. While scrolling through, I noticed "DMSO" and got excited and clicked.

DMSO is known for its ability to penetrate the skin and other biological membranes, making it effective for delivering other substances into the body. It is both water and oil soluble, which allows it to mix with a wide variety of substances. This characteristic makes DMSO useful in various medical and industrial applications.

Applying DMSO on damp skin can indeed expedite its absorption, as water on the skin helps to facilitate its penetration. However, it is crucial to ensure the skin is clean before applying DMSO because any contaminants on the skin can also be absorbed into the bloodstream along with the DMSO.

DMSO has been used to alleviate pain and inflammation related to conditions such as arthritis, strains, sprains, and even for drug extravasation injuries. It also has applications in reducing tissue damage from extravasated chemotherapy drugs and improving conditions like interstitial cystitis.

If you're interested in learning more about DMSO, highly recommend the book "Healing with DMSO" on Amazon.

Thanks for letting me chime in and I cant wait to learn and explore.

I attached the amazon link to the DMSO I recommend and currently have at home! And the book I mentioned!!

Are those affiliated links? Also, transdermal DMT in DMSO has proven to be ineffective - you would need to swim in a bathtub of the stuff to stand a chance of experiencing any significant effects. That sounds like a terrible idea to me.
Since no effects were reported with the DMSO containing DMT covering large parts of the skin, we can be pretty sure it did not penetrate the skin.

 
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