In the 1960s Abbie Hoffman devised his "lace vs. Mace" concept, the notion was that as police forces were coating demonstrators in pepper spray and chemicals against their will, that in retaliation the demonstrators should spray police with a mixture of Lysergic acid diethylamide and Dimethyl-sulfoxide. It was claimed that the DMSO would allow LSD to absorb through the skin, resulting in psychoactivity.

This DMSO/LSD concept was popularized again by the musical group "the dead kennedys"

Also, in a lecture by David E. Nichols, Nichols mentions Nick Sand telling him that DMSO/LSD had no effect:

DMSO does not really work with DMT either, but it's an interesting concept, solvents which would allow transdermal absorption of psychedelic compounds...

-eg