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DMT Fumarate Nosespray - solubility in water?
- Thread starter lorax
- Start date
Observant
Nothing Stops The Void
Yes DMT Fumarate is snortable without MAOI , but the required dose is higher than with freebase DMT or smoked DMT.
SWIM thought about that for some time , and maybe tests this route soon .
He would try it with 5Meo-DMT Bufotenin or Psilocin , assuming one Pump of the Spraybottle could hold around 5mg .
Maybe nnDMT could be worth a try too , then SWIM would consume some kind of MAOI before spraying
SWIM thought about that for some time , and maybe tests this route soon .
He would try it with 5Meo-DMT Bufotenin or Psilocin , assuming one Pump of the Spraybottle could hold around 5mg .
Maybe nnDMT could be worth a try too , then SWIM would consume some kind of MAOI before spraying
Thanks for bringing this up guys. I guy I once met wanted to ask whether anyone has ever tried snorted dmt fumarate in combination with oral MAOIs. One needs around 150mg dmt fumarate up the nose and it is not extremely pleasant but OK. Maybe with MAOIs it can become very intense and it is possible to have a breakthrough for a prolonged amount of time.
Maybe even less dmt fumarate is needed when snorted + oral MAOIs?? 100mg is good to snort, 50mg in each nostril is not really a big deal.
Hmmmmmm.....
Maybe even less dmt fumarate is needed when snorted + oral MAOIs?? 100mg is good to snort, 50mg in each nostril is not really a big deal.
Hmmmmmm.....
Observant
Nothing Stops The Void
Oh , i was thinking about snorting ,maybe several lines , one line consisting of 7+7+7+7 .
You want to dissolve 150mg of Fumarate Salts in a Seawater Nosespray, Right ?
How much water ? Do you know how good the solubility is?
One push of the nosespray bottle has 0,05ml i think
You want to dissolve 150mg of Fumarate Salts in a Seawater Nosespray, Right ?
How much water ? Do you know how good the solubility is?
One push of the nosespray bottle has 0,05ml i think
SWIM has found dmt fumarate does not snort that well..the effects were weak..he was able to get down about 130mg..it was so painful..made him vomit and shit..and the effects were extremely weak
SWIM thinks the only ones worth trying this method out would be bufotenine, 5-meo, and psilocin
this would be a great way for people who are hesitant to smoke SWIY's weird ass drugs that he makes..people are always willing to put something up their nose..rather than smoke some weird as drug
SWIM thinks the only ones worth trying this method out would be bufotenine, 5-meo, and psilocin
this would be a great way for people who are hesitant to smoke SWIY's weird ass drugs that he makes..people are always willing to put something up their nose..rather than smoke some weird as drug
69ron
Esteemed member
I think the best candidate for this would be 5-MeO-DMT. The dose needed is so small (5-15 mg). A very hygroscopic salt would be best, even a deliquescent one if possible. Something like 5-MeO-DMT tartrate is probably very hygroscopic.
5-MeO-DMT snorted is much more pleasant than smoked 5-MeO-DMT. It’s more similar to mescaline and LSD than smoked 5-MeO-DMT in SWIM’s opinion.
If you make a 5-MeO-DMT nasal spray, please keep the dose on the low side. 5-MeO-DMT is a little too mind blowing for some people. A high dose can be really freaky, and could scare the crap out of your friends.
5-HO-DMT (bufotenine) is much more active nasally than DMT, far friendlier, with the dosage ranging from 25-75 mg. 5-HO-DMT is the most friendly of all psychedelics. I think it’s impossible to have a bad trip on it. A good amount is 50 mg. But it needs to be freebase, or the effects are not very good. 5-HO-DMT is said to be soluble in alkali, but will react with the alkali if the pH is too high. I don’t know what a safe alkaline pH is for long term storage. pH 12 is not safe. At pH 12 it will react with the alkali within 24 hours possibly forming dehydrobufotenine. However, dehydrobufotenine might be active nasally.
I’d recommend adding 7 mg of harmaline. It will increase the potency by 2 times and prolong the effects. It makes 5-MeO-DMT more DMT-like, and lessons the “freak out” potential of it.
5-MeO-DMT snorted is much more pleasant than smoked 5-MeO-DMT. It’s more similar to mescaline and LSD than smoked 5-MeO-DMT in SWIM’s opinion.
If you make a 5-MeO-DMT nasal spray, please keep the dose on the low side. 5-MeO-DMT is a little too mind blowing for some people. A high dose can be really freaky, and could scare the crap out of your friends.
5-HO-DMT (bufotenine) is much more active nasally than DMT, far friendlier, with the dosage ranging from 25-75 mg. 5-HO-DMT is the most friendly of all psychedelics. I think it’s impossible to have a bad trip on it. A good amount is 50 mg. But it needs to be freebase, or the effects are not very good. 5-HO-DMT is said to be soluble in alkali, but will react with the alkali if the pH is too high. I don’t know what a safe alkaline pH is for long term storage. pH 12 is not safe. At pH 12 it will react with the alkali within 24 hours possibly forming dehydrobufotenine. However, dehydrobufotenine might be active nasally.
I’d recommend adding 7 mg of harmaline. It will increase the potency by 2 times and prolong the effects. It makes 5-MeO-DMT more DMT-like, and lessons the “freak out” potential of it.
Back on new years day swim insufflated a good amount of freebase 5meo, dosage unknown (he just eyeballed a "good amount," whatever that is). It was quite a ride, very pleasant aside from that synthetic vibe that swim's not crazy about. He wants to try natural 5meo some day but is still waiting for a good tek to be developed to isolate it. It hella burned, probly a salt would be better for that.
69ron, 'twas my understanding that freebase bufo didn't cross the blood-brain barrier too well, and that this was responsible for unpleasant physiological side effects (turning purple, etc). I thought the idea was to calcify the bufo into calcium bufotenate, which according to reports I've read is -the- ultimate tryptamine compound. Swim has yet to try it, he was gonna on new years but the pipe he'd loaded with it ended up getting used by someone else. A friend who forgot the calcium bufotenate was on there loaded up some n,n dmt on top of it and gave it to a first-timer to try. Blew their phuqin' mind! She freaked out pretty badly, said there was a three-headed god whispering so loud she couldn't hear what it was saying...
Anyway that's why swim snorted the 5meo instead.
Also, 'twas my understanding that 5meo in conjunction with an maoi was rather dangerous? Probly what you recommend would be fine, 7mg harmaline ain't that much... but I've heard one needs to be very careful with this combo. The only case I know of regarding any huasca-type death (besides the nicotine poisoning case) was an overdose of 5meohuasca, but granted that was with a ridiculously huge amount of 5meo. Homedude probly thought he had n,n or something...
69ron, 'twas my understanding that freebase bufo didn't cross the blood-brain barrier too well, and that this was responsible for unpleasant physiological side effects (turning purple, etc). I thought the idea was to calcify the bufo into calcium bufotenate, which according to reports I've read is -the- ultimate tryptamine compound. Swim has yet to try it, he was gonna on new years but the pipe he'd loaded with it ended up getting used by someone else. A friend who forgot the calcium bufotenate was on there loaded up some n,n dmt on top of it and gave it to a first-timer to try. Blew their phuqin' mind! She freaked out pretty badly, said there was a three-headed god whispering so loud she couldn't hear what it was saying...
Anyway that's why swim snorted the 5meo instead.
Also, 'twas my understanding that 5meo in conjunction with an maoi was rather dangerous? Probly what you recommend would be fine, 7mg harmaline ain't that much... but I've heard one needs to be very careful with this combo. The only case I know of regarding any huasca-type death (besides the nicotine poisoning case) was an overdose of 5meohuasca, but granted that was with a ridiculously huge amount of 5meo. Homedude probly thought he had n,n or something...
calcium bufotenate is not proven to exist..and the salt forms of bufotenine are what cause the unpleasant side effects...while freebase bufotenine works wonderful..SWIM hasnt had any negative side effects from freebase bufotenine..except some nausea from impure bufotenine...and slight vasoconstriction..which is easily taken care of with some theobromine..or THH
69ron
Esteemed member
Freebase burns like HELL, even when taken sublingually. I don’t recommend it. SWIM uses 5-MeO-DMT fumarate usually. That doesn’t burn at all when taken sublingually, not even a little bit. The trip is also longer and more euphoric, and more LSD/mescaline like. Because it’s a salt, it absorbs more slowly and that changes the effects a little bit.SyZyGyPSy said:
SWIM gets lots of auditory effects from freebase bufotenine. Lots. He loves it. Can’t say much about calcium bufotenate though. SWIM tried making it and the bufotenine decomposed. Possibly the pH was too high and it decomposed to dehydrobufotenine? I’m not sure. At any rate, freebase bufotenine is VERY NICE. Virtually free of side effects for SWIM.SyZyGyPSy said:
I don’t know how factual that is. SWIM has used 5-MeO-DMT with harmaline, harmine and also THH quite a few times. SWIM never felt any toxic effects from it. In South America some ayahuasca is made with chaliponga and caapi only. Chaliponga contains both DMT and 5-MeO-DMT, and sometimes a lot of 5-MeO-DMT. SWIM has made ayahuasca (as well as pharmahuasca) using chaliponga and never felt any hint of toxic effects from the combination. Until more data is available, I wouldn’t put too much weight on that, but I would also be on the cautious side and not take too much 5-MeO-DMT. Even on it’s own without an MAOI, 5-MeO-DMT is said to produce some unusual toxic reactions in some people. It hasn’t been studied that much. It’s safety isn’t that well known.SyZyGyPSy said:
Synthesized DMT HCL only required maybe 30 mg to be juuuuust on the edge of breathrough and 35 would do it. I found it incredibly visual, astounding, more reliable than smoking, and it lasted longer.
It only burned the nose BELOW a certain threshold... like.. 15 mg burned like hell, whereas 25 I couldn't feel. Even before it kicked in... small amounts would instantly hurt, large amounts never gave much discomfort. No idea why.
My friends shared the same sort of dose requirements. I would be very careful before jumping off the deep end with it.
It only burned the nose BELOW a certain threshold... like.. 15 mg burned like hell, whereas 25 I couldn't feel. Even before it kicked in... small amounts would instantly hurt, large amounts never gave much discomfort. No idea why.
My friends shared the same sort of dose requirements. I would be very careful before jumping off the deep end with it.
69ron
Esteemed member
Jorkest said:
Some people find it extremely visual, but most don't. For SWIM it is mildly visual producing swirling melting type of visual distortions, but no true visions. With eyes closed the visuals are dark and distant, very unlike DMT. But that’s SWIM. Some people get full brown visions from it.
For SWIM, DMT-like visions are possible if its mixed with harmaline.
SWIM has had out of body experiences with 5-MeO-DMT alone.