I'm not sure if dosage is in fact such an important factor. My first experience of DMT was with 60 mg with breakthrough and total ego loss. Since then I've found 35 mg is normally sufficient for breakthrough although it's even happened at 25 mg.

Regarding ego loss I think this has far more to do with attitude as you enter. You have somewhere (don't ask me where!) the choice to fully enter into the experience, accept everything, in which case ego disappears. You also have the choice to be a witness to the experience which in my opinion is surrender with one hand on the lifeboat (in case you want to change your mind later). And then there's fighting the experience - just don't go there

The value of complete ego loss, in my humble opinion, is that it absolutely robs you of any context. All these problems we hang on to, anxiety / fears / depressions / etc, get their fuel from the belief that our life is real. The wonder of losing all context for this life is that we see (it is seen) that what we thought of as real is simply a version, an interpretation, a convenient method of looking at things in order to survive. OK, so a lot of that is going to return after the experience but it's never going to be 100% believed again. Use all kinds of dosages to explore this. No harm in taking three/four different doses in an afternoon with much reflection in between (but don't let anyone know I said that :d )