Professor_Fungus
Rising Star
https://www.mdpi.com/1424-8247/18/3/380
"We recommend the use of ultrasonic-assisted extraction (UAE) as the most effective technique, given its ability to maximize yield through cavitation effects that promote efficient cell wall disruption. The optimal solvent for psilocybin extraction is methanol acidified with acetic acid or hydrochloric acid, which has been shown to enhance compound solubility while preventing psilocin degradation. The recommended solvent-to-material ratio is at least 1:100 (m/v), as higher ratios improve compound recovery"
This makes me really suspicious of the paper. Does anyone have any references that show dephosphorylation in acidic conditions? I have somebody telling me that acidic methanol is the best extraction solvent. Find that very hard to believe cuz that seems like a great way to convert to psilocin
"We recommend the use of ultrasonic-assisted extraction (UAE) as the most effective technique, given its ability to maximize yield through cavitation effects that promote efficient cell wall disruption. The optimal solvent for psilocybin extraction is methanol acidified with acetic acid or hydrochloric acid, which has been shown to enhance compound solubility while preventing psilocin degradation. The recommended solvent-to-material ratio is at least 1:100 (m/v), as higher ratios improve compound recovery"
This makes me really suspicious of the paper. Does anyone have any references that show dephosphorylation in acidic conditions? I have somebody telling me that acidic methanol is the best extraction solvent. Find that very hard to believe cuz that seems like a great way to convert to psilocin
