FDA approves Ecstasy !

[sigmundfreuid]

FDA approves Ecstasy : New treatment of Iraq war veterans with resistant PTSD . Encouraging results


This is really great news !

 

[Virola78]

Love heals

 

[Touche Guevara]

Anyone found a link to a source on this? The article doesn't cite a press release or anything :?

 

[TheNtt]

Anyone found a link to a source on this? The article doesn't cite a press release or anything :?

MAPS is currently working on numerous MDMA therapy studies. Check it out here: MDMA - Multidisciplinary Association for Psychedelic Studies - MAPS

Where I live they have already held the first training session for Doctors to be trained in giving MDMA therapy. The military is backing it. The FDA is backing it. It shouldn't be long before clinical MDMA is legal for people with conditions like PTSD.

 

[ubu]

Good news. There was a rumor (study?) regarding the neurotoxicity of MDMA. What happened to it?

 

[SnozzleBerry]

This is kind of old, MAPS has been "playing around" with this for a moment.

Good news. There was a rumor (study?) regarding the neurotoxicity of MDMA. What happened to it?

Are you referring to the old government-funded studies in which the scientist fudged the results of the first one and then used methamphetamine instead of mdma in the second one to claim that mdma causes Parkinson's?

 

[ubu]

Are you referring to the old government-funded studies in which the scientist fudged the results of the first one and then used methamphetamine instead of mdma in the second one to claim that mdma causes Parkinson's?

What a pathetic! And they often succeed in fooling the society with this kind of "scientific" study. Fortunately some lies has short legs.

 

[Virola78]

Neurotoxicity of MDMA was never proven?? Doesnt MDMA destroy certain parts of certain neurons?

From what i have understood it remains unclear what effects this type of destruction has on the human brain functions. Which is imo reason enough to do more research. After all it is in the interest of public health to know more of the riscs associated with drugs. I dont think the guys that sign up for the treatment think they have much to loose (in terms of 'quality of life'.) Win-win.

 

[SnozzleBerry]

Neurotoxicity of MDMA was never proven?? Doesnt MDMA destroy certain parts of certain neurons?

From what i have understood it remains unclear what effects this type of destruction has on the human brain functions. Which is imo reason enough to do more research. After all it is in the interest of public health to know more of the riscs associated with drugs. I dont think the guys that sign up for the treatment think they have much to loose (in terms of 'quality of life'.) Win-win.

I know there was a study that showed mdma caused dendrites to either rescind or get shorn off or something, I can't remember which one, Mckenna referenced it in at least one of his talks. According to wikipedia and the papers referenced in the article, there is not conclusive proof that mdma, when taken infrequently and at reasonable doses, is irreversibly neurotoxic.

Some studies show that MDMA may be neurotoxic in humans.[107][108] Other studies, however, suggest that any potential brain damage may be at least partially reversible following prolonged abstinence from MDMA.[106][109] However, other studies suggest that SERT-depletion arises from long-term MDMA use due to receptor down-regulation, rather than true neurotoxicity.[110] Depression and deficits in memory have been shown to occur more frequently in long-term MDMA users.[111][112] However, some recent studies have suggested that MDMA use may not be associated with chronic depression.[113][114]


Several studies have indicated a possible mechanism for neurotoxicity in a metabolite of MDMA, through the reaction of Alpha-Methyldopamine, a principle metabolite, and Glutathione, the major antioxidant in the human body. One possible product of this reaction, 2,5-bis-(glutathion-S-yl)-alpha-methyldopamine, has been demonstrated to produce the same toxic effects observed in MDMA, while MDMA, and alpha-methyldopamine themselves have been shown to be non-neurotoxic. It is however, impossible to avoid the metabolism of MDMA in the body, and the production of this toxic metabolite.[123][124][125] Some studies have demonstrated possible ways to minimize the production of this particular metabolite, though evidence at this point is sparse at best.

The government study I referenced earlier was done by Riccaurte and some others and there's an outstanding paper done in response by Rick Doblin and several other people related to MAPS; you can find it on their website and it's great reading.

 

[Apoc]

I don't know why they aren't using mescaline instead of, or in addittion to mdma. They know the effect is similar and without the potential negative physical effects. I suspect allowing mescaline for soldiers would be quite insulting to native Americans who have tried to claim religious right, and been thrown in jail. I suspect those people probably have some ptsd.

 

[shoe]

This is quite interesting.... Ann shulgin is proud I bet.

 

[Virola78]

@ SnozzleBerry

Yea man, that is the research i was refering to.
Thx...

Funny how in these days of abundant information on any subject i find myself getting used to knowing 'where' to find certain inforamtion.. instead of remembering all the actual information in details. Im i lazy or efficient? i hope both ; )