ObsidianKnife said:@Parshvik Chintan + @The Traveler – there are surely dangers (psychologically + life-threatening) in administering an maoi in combination with an entheogen in a self-experimentation scenario (ie, overdosing 'by accident')?
I think perhaps what they're getting at is why it is you believe that the MAOI would only be a dangerous combination when ingested in the "Western" fashion as you put it as opposed to say ayahuasca where equal amounts of either DMT or the harmala alkaloids may be consumed. There seems no logical reason you could offer why it should be more dangerous when the extracts are taken versus what equates to the same dosage in brews (of which brews at such doses are consumed regularly). Furthermore your speculation clearly shows no basis in facts, for you have no evidence to offer to support your point. While there are many physical dangers with "irreversible MAOIs" the harmala alkaloids are RIMAs (short-term/reversible) and do not present many of the same dangers associated with other MAOIs such that dietary restrictions are really more lenient than they appear to be.