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Freebase 4-HO-MiPT?

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PH0Man

PH0Man

Rising Star
Hey all,

So...freebase 4-HO-MiPT?

1) It's very unstable in water so how would one convert the salt into a freebase without using water and destroying the product (if indeed this would be a problem)?

2) 4-HO-MiPT seems to have the potential for being quite a bit more powerful than DMT, considering only 15-25mgs offers a good 2-6 hour trip (almost 10 times less than DMT orally)

3) Considering how power it is orally, vaporized 4-HO-MIPT might be incredibly powerful and long lasting.

Thoughts?

Cheers,
Marc
 
AFAIK all 4-HO trypts are too instable to be smoked. I heard of some people with a bit success, but then they did need excessive amounts of it to compensate for all the losses due to smoking. But I haven't occupied myself much with this topic.
Maybe an inert atmosphere would help???

And IMHO potency isn't equivalent to how powerful a substance is. E.g. LSD is extremely potent needing only 100ug for a trip and 1000ug=1mg would be the extreme. But still from reports, many people having done this still say other substances, e.g. like DMT or 5-Meo-DMT were more "powerful" to them.

If you want to have it "longer lasting", you could also use just MiPT. This can be smoked. Or use MAOIs with DMT...

Edit:
Just found this thread:

So it seems, smoking could be possible.
Are you sure, that water will immediately kill it? I think I once read, that it isn't good for storage, but then it shouldn't be a big problem to have a quick dive just for FBing.

According to this thread:

4-HO-DMT really has some problems with water, especially alkaline (I would think 4-HO-MiPT is similar). But is soluble in ethanol. So I would think it should work in there. Anyone of the chemists knows if FBing can be done in ethanol?

Anyways. In this thread is also an instruction how to FB Psilocin from Methanol. It seems there a little bit of water is needed. But probably not too problematic.
I would expect the same works for 4-HO-MiPT.
BTW: There are also reports in this thread about smoked 4-HO-DMT and as it seems duration like that is much shorter and effects much milder. So I wouldn't expect this to be much different for the MiPT version.
 
You could freebase it without water using something like chloroform and ammonia

I dont think its a good idea to smoke it. When its unstable even in water the slightest amount of heat will destroy it.

Also how did you get the idea that 4-HO-Mipt is strong just because it has a long duration?
Most of the tryptamines dose at ~25mg with some outliers that need more like the DIPT DALT variants and DPT.
Most people class the strenght not by the duration but by the trip itself. 25mg of most 4-HO substituted tryptamines will give you half a day of full effects but they are still just weak effects.

Also dont forget that smoking a drug usually shortens the effects. Same is for snorting.
 
if it's that unstable in water, then its even more unstable when heated. Freebase themselves of all the 4-ho trpytamines degrade quickly.

It's a potent drug, if you were to try to vaporize 10mg of it you might get <1mg with a bunch of side products, but it will still give you effect.

But there is no benefit to doing this, it doesn't change the effect of the drug. Even when taking these compounds by IV, it usually takes roughly the same amount of time for the effects to peak, about 20 minutes. The required dosage is just slightly smaller. Better to take it orally.
 
Mindlusion said:
But there is no benefit to doing this, it doesn't change the effect of the drug. Even when taking these compounds by IV, it usually takes roughly the same amount of time for the effects to peak, about 20 minutes. The required dosage is just slightly smaller. Better to take it orally.
Click to expand...

Thanks for the info :) Definitely no point in smoking the stuff if taking it IV doesn't do much.
What would be the reason for DMT's very different effects when taken orally vs IV, compared to miprocin's negligible differences?
 
PH0Man said:
Mindlusion said:
But there is no benefit to doing this, it doesn't change the effect of the drug. Even when taking these compounds by IV, it usually takes roughly the same amount of time for the effects to peak, about 20 minutes. The required dosage is just slightly smaller. Better to take it orally.
Click to expand...

Thanks for the info :) Definitely no point in smoking the stuff if taking it IV doesn't do much.
What would be the reason for DMT's very different effects when taken orally vs IV, compared to miprocin's negligible differences?
Click to expand...

Hard to say exactly, actually. You would think the onset is due to rapid administration, which it is... So you might expect the same thing with any psychedelic administered rapidly.

But this is not the case, the rapid onset of psychedelic effect does not always correlate with rapid administration. Often what happens is the physiological effects hit immediately, BP rise, HR rise, but they psychedelic effects themselves still take some time to build, 15-20 minutes usually. Some that come to mind are EPT and DET. LSD has been administered IV and it behaves the same. The 4-HO analogues follow suit, my guess is that psilocin does the same...

In other cases, the psychedelic effects hit hard and fast, like with DMT, or 5-meo-DMT. Synthetic ones like MPT and DPT (although this is a bit different) do too.

Although... Its not that black and white, if you eat enough psilocin, it hits like a ton of bricks.

And if you eat enough DMT orally, you can have the breakthrough experience, you will at some point reach the same place...
 
Mindlusion said:
...
Click to expand...
Thank you for this information :)

If I had to guess, I would theorize that the rapidity of onset has to do with how fast the brain 'absorbs" a particular substance, and that with DMT and 5-Meo-DMT, the brain "absorbs" the substances very quickly, perhaps because it "recognizes" them somewhat...this would also explain why the duration is so ephemeral.

Do you know of any substances that have a very rapid onset but a long duration? I can't think of any..
 
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