Harmalas are tricky compounds . I don´t find them particularly enjoyable since even with a perfect diet, and prolonged abstention of medicines and drugs that react badly with them it still had bad body loads and was damn uncomfortable.
I suppose lower doses, and more frequently would make one more tolerant to these nasty side effects but I´ve only used harmalas to orally activate DMT, which I suppose is your goal also.
Perhaps try that? I´ve read about people drinking rue seed tea every day, and eventually building it up in their system because of the long half-life yet avoiding all or most of the side effects associated to it.
It seems that this way you get the best out of the both worlds. You get to make the DMT orally active, but don´t get sick in doing so. At least that´s what I heard.