Alright guys I gotta chime in here. Combining coffee with high doses of harmaloids is not a good idea. 

Both increase your heart rate. Coffee also has some MAOI effects. Combining to two has been responsible for hospitilizing an individual. Although no death has been reported its not a smart combination. As kemists experience shows it should be avoided. Just because some of you can combine the two doesn't mean everybody can or should. There is no reason too the effects of rue are strong enough on their own. Someone who has heart problems or is older could seriously be putting their life at risk.