People with problem substance use have found that larger doses of ibogaine can significantly reduce withdrawal from opiates and temporarily eliminate substance-related cravings.
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By some estimates, ibogaine use has a mortality rate of about 1 in 300. Deaths from ibogaine have been attributed to bradycardia (slowing of the heart), lethal combinations with other substances, liver problems, and other conditions. Anyone interested in using ibogaine to treat substance abuse should carefully weigh the risks and benefits of treatment, and should ensure that medical assistance is available during the session.
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Ibogaine Therapy - Multidisciplinary Association for Psychedelic Studies - MAPS
MAPS has completed two observational studies of the long-term effects of ibogaine treatment on patients undergoing therapy at independent ibogaine treatment centers in Mexico and New Zealand. Image: Christopher Hansen Data from these studies contribute to the growing scientific literature about...www.maps.org
Preclinical research has generally supported anecdotal claims that ibogaine attenuates withdrawal symptoms and reduces drug cravings. Concerns about ibogaine's safety, as well as a dearth of solid data from human studies, have hampered progress in its development as an approved medication. This article outlines major findings from preclinical studies, discusses concerns about ibogaine's safety, and details previous and ongoing research on ibogaine's use as an anti-addictive treatment for humans.
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Ibogaine in the treatment of substance dependence - PubMed
Ibogaine is a psychoactive alkaloid derived from Tabernanthe iboga, a plant used in initiatory rituals in West Central Africa. Largely because of ibogaine's status as a Schedule I substance in the U.S., the development of ibogaine's use in the treatment of drug addiction took place outside...www.ncbi.nlm.nih.gov