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Is it safe to do 2 instead of 3 boils for ayahuasca?

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Godsmacker

Rising Star
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Hello, my friend recently decided to make some ayahuasca/anahuasca in a slow cooker using ACRB and syrian rue (28:6 gram ratio). He plans to do two four hour boils instead of three three hour boils before reducing. Would doing only two boils as opposed to three weaken the potency of his brew? Is a third boil really that necessary so as long as longer boils were done before hand? Thank you very much for your help.
 
Isn't it really more about how many times you extract, due to chemical equillibrium?
I ask because I'm not 100% sure, but it is my understanding so far that volume doesn't matter that much - rule of thumb is usually to do small but many extractions, rather than 1 big.
(of course 3 is the golden number, and a 4th doesn't hurt)

Even though the water from the first pull theoretically could hold all the DMT from the bark, equillibrium would leave some DMT behind in the ACRB. By draining and adding new water, the equillibrium changes so can extract further DMT from the material..
 
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