Want to summarize the Crystals In Solvent Lazily OTC (CISLO) systems that are showing promise. These are less general than liquid - liquid A/B extractions with a lot fewer working combinations, but the specialization makes the process shorter/simpler when it does work.
The general method is:
- Make a paste with dry plant material, water, and base
- Pull with solvent
- Reccomended: Purify solvent with rest to settle particles and/or a drying agent to remove water/micro emulsions (drying agent is not needed in all cases). Decant or filter. With experience and an ideal system, this step can potentially be skipped to achieve legendary lazyness status, but it can be good "insurance" as more experience is gained.
- Salt solvent with an acid that is soluble in the solvent and that will react and form xtals with the dissolved alkaloids of interest. These requirements really limit the material space, and a lot of calories have been spent with trial and error here. Most combos don't work, but the combos that work result in a specialized simplified extraction compared to the general A/B method that accepts many more different materials. The loss of generality and need for very specific material is rewarded with ease of extraction combined with instant selectivity/purity.
- Rest so beautiful crystaline product forms directly in pulled solvent. Recover salts by decanting and wash with fresh solvent to remove any traces of salting acid and solvent soluble plant material. If using toluene, a second solvent such as acetone is reccomended to wash away toluene itself.
With the advent of e-vaping, some of these salts can be administered via aerosol into the lungs near physiological pH as long as the salts are soluble in PG (some are, but not all). This "salty" method is a new alternative to the classic vaporization of free base alkaloids with heat. Warning that some organic salts like citric can breakdown at vaping temps (175C to 200C) and vaping safety is has not been established.
There are currently three main CISLO families:
- CIELO: Ethyl acetate salted with an organic acid (such as citrate or fumaric). Success reported for mescaline from columnar cactus and harmalas from rue seeds. Did not work for DMT from MHRB or psilocybin from mushrooms.
- CILLO: Limonene salted with benzoic acid. Worked for DMT. Did not work for mescaline. Needs to be tested psilocybin.
- CINLO: Naphtha salted with benzoic acid. Worked for DMT.
- CITLO: Toluene salted with benzoic acid. Worked for mescaline in preliminary testing. Needs to be tested for DMT and psilocin.
Links to example CISLO systems (some are finalized, others are work in progress):
- CIELO Mescaline Citrate/Fumarate: Cactus/Lime/Ethyl Acetate/Citric or Fumaric acid - confirmed
- CITLO Mescaline benzoate: Cactus/Lime/Toluene/Benzoic acid. Another example here.
- CIELO Harmala citrate: Rue/Lime/Hot Ethyl Acetate/ citric acid - confirmed
- CILLO DMT benzoate: MHRB powder/Lye/Limonene/Benzoic acid - work in progress, so far promising
- CINLO DMT Benzoate and possibly something else: MHRB powder/Lye/Naphtha/Benzoic acid - work in progress, so far promising
- CITLO DMT benzoate: MHRB/Lye//Ethyl Acetate/Benzoic acid
- CIALO Bufotenine benzoate: Yopo/Sodium Carbonate/Acetone/Benzoic acid
Hope we can confirm these and add other systems over time. Cheers and happy xtal growing
The general method is:
- Make a paste with dry plant material, water, and base
- Pull with solvent
- Reccomended: Purify solvent with rest to settle particles and/or a drying agent to remove water/micro emulsions (drying agent is not needed in all cases). Decant or filter. With experience and an ideal system, this step can potentially be skipped to achieve legendary lazyness status, but it can be good "insurance" as more experience is gained.
- Salt solvent with an acid that is soluble in the solvent and that will react and form xtals with the dissolved alkaloids of interest. These requirements really limit the material space, and a lot of calories have been spent with trial and error here. Most combos don't work, but the combos that work result in a specialized simplified extraction compared to the general A/B method that accepts many more different materials. The loss of generality and need for very specific material is rewarded with ease of extraction combined with instant selectivity/purity.
- Rest so beautiful crystaline product forms directly in pulled solvent. Recover salts by decanting and wash with fresh solvent to remove any traces of salting acid and solvent soluble plant material. If using toluene, a second solvent such as acetone is reccomended to wash away toluene itself.
With the advent of e-vaping, some of these salts can be administered via aerosol into the lungs near physiological pH as long as the salts are soluble in PG (some are, but not all). This "salty" method is a new alternative to the classic vaporization of free base alkaloids with heat. Warning that some organic salts like citric can breakdown at vaping temps (175C to 200C) and vaping safety is has not been established.
There are currently three main CISLO families:
- CIELO: Ethyl acetate salted with an organic acid (such as citrate or fumaric). Success reported for mescaline from columnar cactus and harmalas from rue seeds. Did not work for DMT from MHRB or psilocybin from mushrooms.
- CILLO: Limonene salted with benzoic acid. Worked for DMT. Did not work for mescaline. Needs to be tested psilocybin.
- CINLO: Naphtha salted with benzoic acid. Worked for DMT.
- CITLO: Toluene salted with benzoic acid. Worked for mescaline in preliminary testing. Needs to be tested for DMT and psilocin.
Links to example CISLO systems (some are finalized, others are work in progress):
- CIELO Mescaline Citrate/Fumarate: Cactus/Lime/Ethyl Acetate/Citric or Fumaric acid - confirmed
- CITLO Mescaline benzoate: Cactus/Lime/Toluene/Benzoic acid. Another example here.
- CIELO Harmala citrate: Rue/Lime/Hot Ethyl Acetate/ citric acid - confirmed
- CILLO DMT benzoate: MHRB powder/Lye/Limonene/Benzoic acid - work in progress, so far promising
- CINLO DMT Benzoate and possibly something else: MHRB powder/Lye/Naphtha/Benzoic acid - work in progress, so far promising
- CITLO DMT benzoate: MHRB/Lye//Ethyl Acetate/Benzoic acid
- CIALO Bufotenine benzoate: Yopo/Sodium Carbonate/Acetone/Benzoic acid
Hope we can confirm these and add other systems over time. Cheers and happy xtal growing