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Legal DMT(almost)

Migrated topic.
I actually first read it in a .pdf file here on the nexus. That does kind of explain things, maybe the author half assed what Shulgin wrote and claimed it as fact.
EDIT: wow, I just noticed that I said "you'd essentially synthesize DMT in your stomach" in my first post, no wonder the hostility, that was a complete idiotic mistake right there, I didn't read that claimed at all.
 
Hmmm, I think the primary source that feeds those links Drainlife posted is some ancient Phalaris type tek hanging on the net somewhere, I'll dig out the link tommorow.
 
drainlife20 said:
I actually first read it in a .pdf file here on the nexus. That does kind of explain things, maybe the author half assed what Shulgin wrote and claimed it as fact.
EDIT: wow, I just noticed that I said "you'd essentially synthesize DMT in your stomach" in my first post, no wonder the hostility, that was a complete idiotic mistake right there, I didn't read that claimed at all.
Click to expand...

ooOoo..yeah, that pdf actually suggests it, i wouldn't. you may get side effects from other metabolites, and an MAOI will just help them stay around longer.

I understood your statement, so I didn't give you any flack. the epithelial cells in the gut and surrounding tissues synth serotonin and its metabolites. dmt is currently thought to be mainly produced in peripheral (non-neural) tissues, where INMT is expressed.
 
yea sorry I flew off the handle, this post just reeked of some new crazy way to get high and sounded more like something that would make you ill or worse.

The crazy things kids do these days to get high just get on my nerves a bit.

I mean seriously imagine enriching some crazy molecule from wood bark (which is present at less than 1%!) that supposedly transports you to another dimension and back in less than 15 minutes. Now how crazy is that :lol:
 
This is the document I was thinking of: http://diseyes.lycaeum.org/dmt/trypcarr.txt

Self-Synthesis of DMT Derivatives

Tryptamine derivatives and beta-Carbolines have been detected as
endogenous metabolites in mammals, including humans. Methyl transferases
that catalyze the synthesis of tryptamines, including DMT, 5-MeO-DMT and
bufotenine, are found in human lung, brain, cerebrospinal fluid, liver
and heart (McKenna & Towers 1984). In the pineal gland MAO is the primary
inactivation pathway of serotonin, a neurotransmitter synthesized from the
amino acid tryptophan. If MAO is blocked by harmine, harmaline or other MAO
inhibitors serotonin can be converted by the methyltransferase enzymes
HIOMT and INMT into psychedelic tryptamines (serotonin --(HIOMT)-->
5-MeO-trypt. --(2*INMT)--> 5-MeO-DMT).

So, ingesting l-tryptophan to increase serotonin levels, a candy bar to
increase the amount of tryptophan getting to your brain and natural
plant material containing 25-50 mg harmine/harmaline to block MAO, all at the
same time, is supposed to cause your pineal gland to synthesize substantial
amounts of 5-MeO-DMT (Most 1986). This is extremely dangerous for persons
with existing amine imbalance or schizophrenia. For normal, healthy people
possible consequences are bad.

A potent inhibitor of INMT, which is a necessary enzyme for the synthesis
of DMT and 5-MeO-DMT, is found in particularly high concentrations in the
pineal gland. A bypassing or inhibition of the synthesis of this inhibitor
might be responsible for trances and other psychedelic states achieved
"without drugs" (Strassman 1990). See Strassman's article for more info and
speculation about the pineal gland.
Click to expand...
 
It is reasonable to believe that to get the body metabolizing DMT in large amounts, you would have to get it in a state, more alien, then the state produced by this substances themselves. It can never be as pleasant as just taking something. there's this story of a man becoming so addicted to the endorphin high that he started to chop of organs; toes, feet, etc. It's probably a myth, or at least i hope for this guy that he never realy existed. But i mean, only when you put yourself in extreme circumstances, the body does these kind of things.
 
Thanks for clearing that up a bit guys. I may be naive, but I'd like to believe there aren't that many people running around spreading misinformation just for kicks. I'm gonna ask around and see if I can find anybody on prescription maoi's, see if I can get some people to test this out. SWIM is a big wimp and would never take one.
 
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