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Lophocereus schottii

Migrated topic.
"As potent as peyote" in regards to sheer alkaloid concentration, yes, but it is not mescaline. Most of the alks are tetrahydroisoquinoline alks, the 'accessory' type of alks in peyote. Lophocerine is 1-isobutyl-2-methyl-6-methoxy-7-hydroxytetrahydroisoquinoline, its the third most abundant alkaloid, the second is pilocereine- a trimer of lophocerine, the most abundant alk is piloceredine, a trimer of lophocerine.
I, too, wondered if it might have any activity beyond inducing vomiting or something but the polymeric tetrahydroisoquinolines kind of creep me out, they arent so well known in pharmacology as far as I'm aware.
So I'd love to see a bioassay if one exists.
Dont expect it to be like peyote tho.
 
Its going to be 'active' but that word has such a broad meaning it still might not be something good to ingest.
I'm curious where the comment comparing it to peyote came from?

If someone ever tries this cacti I'd love to hear the outcome. Especially if it did not kill or harm the bioassayist.
I've noticed there are precious few people reporting ingesting saguaro or cardon despite the assorted claims of activity.
 
yep i've heard that it contains more mescaline than peyote in another forum..than i've seen that the alks content actually is not mescaline but a miscellaneus of other PEAs. sorry for that. anyway,its total alk content make it a very interesting cactus to investigate for sure. i hope to see research in future,maybe in animals and not directly on human beings. as KT says, try to ingest weird almost uknown alkaloids could kill you..
 
Interesting..it would be interesting for someone to bioassay, maybe just small quantities to begin with. Even if it doesnt contain mescaline but still has peyote alkaloids it could be brewed in combo with a mesc containing cacti like bridgessi or pachanoi for a experience along the lines of a peyote trip, since peyote itself takes so long to grow and is illegal many places.

Who knows how accurate this is, but here is erowids log for the species:
"L. schottii ( Berger ) -

Native from southern Arizona to northern Mexico. Characterised by a dense clump of erect stems to 5 - 7 meters tall. Stems have 5 to 9 ribs with wooly, whitish areoles bearing 5 conical gray spines. When about to flower, the areoles expand and grow up to 20 spines. This species will tolerate severe droughts if the plant is of good size. White or red nocturnal flowers.

A rare species in cultivation as it cannot tolerate high Summer temperatures. Propagate from seed or shoots. Shoots from mature and acclimatized plants stand a much better chance of surviving.

Contains: lophocereine, pilocereine.
"
 
Its the non peyote alkaloid content that seems likely to be perceptible.
The most prevalent alkaloid is a trimeric isoquinoline so it would be good to start really low and stay mindful for any signs of neurotoxicity as the dosage increases.
 
This plant is easily propagated but people often kill it. Thinking it wants full sun is probably the most common problem.
In nature is occurs in some really hot zones (overlay the comment on it not wanting high summer temps onto the comment for its occurrence being Southern AZ and northern Mexico and I suspect a minor conflict may emerge?) but it is typically located in at least a partly shaded situation, often in a brushy ravine with abundant plant detritus so it enjoys a richer soil and more moisture than would be anticipated.
 
I would really love to get one of these. Specifically a monstrose form. I had no idea they had peyote related alkaloids in them. And I thought I knew of all the active cacti species.
 
I ordered a lophocereus schotii monstrose cutting. If anyone wants to test a piece of it via tlc let me know and i can provide a sample.
 
great thing hostilis! let's test this guy..nom nom! lol 😁
post a pic when it comes..theese are seriously sexy looking cacti! :lol:
 
They really are beautiful!
 

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I would never want to eat one of those beauties! They're too pretty.

Anyways, thanks to dreamer, we will soon have TLC results from my l. schotii monstrose clone. Along with some other things like l. jourdaniana and myrtillocactus geometrizans. I'll let you all know the results soon.

hostilis
 
Unfortunately the TLC done on my lophocereus schotii came back inconclusive. :( I didn't provide a big enough sample I guess.
 
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