bionecrosis
Rising Star
How many days should pass befor I take mimosa+rue.
Contraindication sith Mdma?pitubo said:The contraindications apply to rue and caapi, not to mimosa.
bionecrosis said:Contraindication sith Mdma?pitubo said:The contraindications apply to rue and caapi, not to mimosa.
MDMA is not a serotonin reuptake inhibitor, actually it's mechanism of action is quite the opposite, it basically busts open the door on that SERT pathway that normally only allows serotonin reuptake in serotonin specific neurons. This means any neurotransmitter present in the synapse can get into the neuron. These other neurotransmitters oxidize inside the cell and kill it. This is roughly the process by which MDMA causes neurotoxicity. In fact, taking an SSRI on the MDMA comedown has been demonstrated to largely prevent neurotoxicity in rat studies. I provide moar information and references for this here. NOTE: DO NOT MIX SSRI's AND HARMALAS! a little neurotoxicity is better than serotonin syndrome.syberdelic said:MDMA/MDA = SSRI
This is an important point. Harmalas should never be mixed with any kind of reuptake inhibitor (SSRI/SNRI/SDRI/etc) or any kind of neurotransmitter releaser (amphetamines, cathinones, ephedrine, etc) or neurotransmiter precursors (5-HTP, L-DOPA, Tryptophan, etc)syberdelic said:And as a note to the mods, I read somewhere on the Nexus (can't find the page again but it was not just a thread) that Wellbutrin (bupropion) is contraindicated for use with harmalas due to increased risk of seizures. Increased risk of seizures is a risk of Welbutrin alone. After discussing with my psychiatrist, it is still contraindicated but the risk that combining any NDRI with MAOI poses is hypertension.
I sayed that I took 3.1grams 30 later started taking he mimosa capsula.It took about 30min to take all mimosa capsuls.I took 1 more gram rue with the mimosa thats 4gr+10gr.And source is good.What it the problem.The mimosa wasnt very fine powder.It was wil some fibers but it is only the inner barkdreamer042 said:1 gram is rue is generally not sufficient to fully inhibit MAO in most people. 3-4 grams is a moar reliable dose for that.
You don't need 10 grams of mimosa that's extremely overkill, even 5 is moar than most people would want or need, start with 2-3 grams and work up from there, you can always take moar if you are underwhelmed, you can't take less when you are overwhelmed.
Boil the materials 3 times in fresh water for 30 minutes each boil, combine all the boils and reduce to drinkable amount.
Attitude Page - DMT-Nexus WikiWhat it the problem
bionecrosis said:I sayed that I took 3.1grams 30 later started taking he mimosa capsula.It took about 30min to take all mimosa capsuls.I took 1 more gram rue with the mimosa thats 4gr+10gr.And source is good.What it the problem.The mimosa wasnt very fine powder.It was wil some fibers but it is only the inner barkdreamer042 said:1 gram is rue is generally not sufficient to fully inhibit MAO in most people. 3-4 grams is a moar reliable dose for that.
You don't need 10 grams of mimosa that's extremely overkill, even 5 is moar than most people would want or need, start with 2-3 grams and work up from there, you can always take moar if you are underwhelmed, you can't take less when you are overwhelmed.
Boil the materials 3 times in fresh water for 30 minutes each boil, combine all the boils and reduce to drinkable amount.
^ Absolutely this. Invest some time in learning how to appropriately approach and work with these powerful substances. It's not a race or a pissing contest, proceeding hastily and/or carelessly rarely achieves the desired outcome. Honor the process, respect the teachers, be humble, and you may find many rewards waiting for you on this path.You have to do some work on the materials