Neurophysiological/psychological effects of DMT

[MrCraggle]

Can anybody help me out here? I'm interested in how DMT works on our neurones and synapses...and possible theories/knowledge on how these physical actions lead to something so beautifully intangible. Has there been any recent studies into this sort of thing...I think i'm probably asking a lot here!?


Any help or pointers in the right direction would be greatly appreciated!

Craig

 

[MrCraggle]

I do appreciate that there won't be any full explanations, but anything that provides clues would be great?

 

[MrCraggle]

Oh found this interesting article in this forum on the possible role of endogenous DMT

http://www.dmt-nexus.me/forum/resource.ashx?a=370

 

[endlessness]

on the information subforum, there is a sticky thread called 'scientific articles about dmt/ayahuasca/psychedelics' .. theres a few papers there that might interest you

 

[MrCraggle]

Cheers that's helpful!

 

[burnt]

^^Yes specifically a number of new papers have come out talking about the role of endogenous DMT and its activity on a class of neural receptors known as the Trace amine recepters. It appears dmt may be involved in sensory perception.

 

[bufoman]

Here is a great review by David Nichols on the neuropharmacology of hallucinogens. Most stuff is about the 5-HT receptors but some new stuff is coming out on other sites (TAAR, sigma, ...)

http://www.scribd.com/doc/6383333/David-E-Nichols-Hallucinogens