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Ok, for those few people out there that are actually interested, for the most part the oral bufotenine trip was unaltered, except for the complete loss of all nausea during the whole trip, and an alteration at the onset. During the onset, the hyoscyamine was felt before the bufotenine was felt. When the bufotenine effects started, it was a mix of the two. It felt warmer, the very light visual effects were warmer, and there was a very slight boost in psychedelic effects. 100 mg of bufotenine orally is extremely weak, so SWIM didn’t expect much from it. 30 mg of bufotenine sublingually is much stronger than 100 mg orally.

Essentially, this test was performed to find an herb that’s effective at combating the nausea of tryptamine based psychedelics such as oral bufotenine. SWIM was searching for one that did not cloud up the effects or cause sedation. Bufotenine taken orally produces more nausea than LSA and all other popular tryptamine, so it was a good choice for this test. Dramamine, available at the local store in an effective anti-nausea medication, but it clouds up the effects of all psychedelics. SWIM doesn’t like Dramamine at all. Scopolamine and hyoscyamine are the two most effective anti-nausea medications there are. In pure form they are available by prescription only. However they are quite abundant and cheap when sources from various Datura herbs. Scopolamine is a sedative while hyoscyamine is more of a stimulant.

Initially SWIM thought Datura stramonium was high in scopolamine, but after doing lots of research he found out that Datura stramonium is high in hyoscyamine. This is good because Datura stramonium is cheap, widely available, completely legal, and hyoscyamine is preferred over scopolamine for this purpose because it’s not sedating.

The nausea caused by oral bufotenine is produced by the same mechanisms that cause nausea for other tryptamines. Oral bufotenine is the strongest producer of nausea out of all the popular tryptamine psychedelics (LSD, psilocybin, ayahuasca, etc.). So if 1-3 seeds of Datura stramonium are capable of blocking the nausea produces by bufotenine, they should be very effective for the other tryptamines as well. Ayahuasca might be an exception to this because the nausea is normally produces by toxins in the caapi vine. But my guess is that 1-3 Datura stramonium seeds will also completely block the nausea from the vine as well.

<blockquote data-quote="69ron" data-source="post: 3256001" data-attributes="member: 787">Ok, for those few people out there that are actually interested, for the most part the oral bufotenine trip was unaltered, except for the complete loss of all nausea during the whole trip, and an alteration at the onset. During the onset, the hyoscyamine was felt before the bufotenine was felt. When the bufotenine effects started, it was a mix of the two. It felt warmer, the very light visual effects were warmer, and there was a very slight boost in psychedelic effects. 100 mg of bufotenine orally is extremely weak, so SWIM didn’t expect much from it. 30 mg of bufotenine sublingually is much stronger than 100 mg orally.Essentially, this test was performed to find an herb that’s effective at combating the nausea of tryptamine based psychedelics such as oral bufotenine. SWIM was searching for one that did not cloud up the effects or cause sedation. Bufotenine taken orally produces more nausea than LSA and all other popular tryptamine, so it was a good choice for this test. Dramamine, available at the local store in an effective anti-nausea medication, but it clouds up the effects of all psychedelics. SWIM doesn’t like Dramamine at all. Scopolamine and hyoscyamine are the two most effective anti-nausea medications there are. In pure form they are available by prescription only. However they are quite abundant and cheap when sources from various Datura herbs. Scopolamine is a sedative while hyoscyamine is more of a stimulant.Initially SWIM thought Datura stramonium was high in scopolamine, but after doing lots of research he found out that Datura stramonium is high in hyoscyamine. This is good because Datura stramonium is cheap, widely available, completely legal, and hyoscyamine is preferred over scopolamine for this purpose because it’s not sedating.The nausea caused by oral bufotenine is produced by the same mechanisms that cause nausea for other tryptamines. Oral bufotenine is the strongest producer of nausea out of all the popular tryptamine psychedelics (LSD, psilocybin, ayahuasca, etc.). So if 1-3 seeds of Datura stramonium are capable of blocking the nausea produces by bufotenine, they should be very effective for the other tryptamines as well. Ayahuasca might be an exception to this because the nausea is normally produces by toxins in the caapi vine. But my guess is that 1-3 Datura stramonium seeds will also completely block the nausea from the vine as well.</blockquote>

[QUOTE="69ron, post: 3256001, member: 787"] Ok, for those few people out there that are actually interested, for the most part the oral bufotenine trip was unaltered, except for the complete loss of all nausea during the whole trip, and an alteration at the onset. During the onset, the hyoscyamine was felt before the bufotenine was felt. When the bufotenine effects started, it was a mix of the two. It felt warmer, the very light visual effects were warmer, and there was a very slight boost in psychedelic effects. 100 mg of bufotenine orally is extremely weak, so SWIM didn’t expect much from it. 30 mg of bufotenine sublingually is much stronger than 100 mg orally. Essentially, this test was performed to find an herb that’s effective at combating the nausea of tryptamine based psychedelics such as oral bufotenine. SWIM was searching for one that did not cloud up the effects or cause sedation. Bufotenine taken orally produces more nausea than LSA and all other popular tryptamine, so it was a good choice for this test. Dramamine, available at the local store in an effective anti-nausea medication, but it clouds up the effects of all psychedelics. SWIM doesn’t like Dramamine at all. Scopolamine and hyoscyamine are the two most effective anti-nausea medications there are. In pure form they are available by prescription only. However they are quite abundant and cheap when sources from various Datura herbs. Scopolamine is a sedative while hyoscyamine is more of a stimulant. Initially SWIM thought Datura stramonium was high in scopolamine, but after doing lots of research he found out that Datura stramonium is high in hyoscyamine. This is good because Datura stramonium is cheap, widely available, completely legal, and hyoscyamine is preferred over scopolamine for this purpose because it’s not sedating. The nausea caused by oral bufotenine is produced by the same mechanisms that cause nausea for other tryptamines. Oral bufotenine is the strongest producer of nausea out of all the popular tryptamine psychedelics (LSD, psilocybin, ayahuasca, etc.). So if 1-3 seeds of Datura stramonium are capable of blocking the nausea produces by bufotenine, they should be very effective for the other tryptamines as well. Ayahuasca might be an exception to this because the nausea is normally produces by toxins in the caapi vine. But my guess is that 1-3 Datura stramonium seeds will also completely block the nausea from the vine as well. [/QUOTE]