To me it appeared that the incompatibility of aquatica and rue is beyond just tyramine hypertension. Then again I never tried drying and simmering different strains. I did eventually find out that drying and simmering is necessary with all grass when combining with rue. Otherwise a consciousness poison is felt. Like an antinutrient compared to dmt which is a nutrient. I tried drying and simmering the 5 meo dominant strain and it still blocked all psychological processes so it did not help. I also tried it with truncata and it didn't make it functional either.