Potential bufotenine extraction tek?

[h3allth]

Hi,

Sorry I can't make this post in the correct location as I am a new user.

I have been reading many bufotenine extractions and compiled what I believe is a feasible tek for me with my limited available equipment and resources. Would any experienced users of the site be able to confirm whether this is all good theoretically? Bare in mind I'm worse than a novice with this so I have no idea at all. Thank you.


Steps

1 powder inner seeds

2 bake inner seed powder at 120c for 45 mins

3 mix with equal portion of sodium carbonate and enough water to create a uniform doughy paste

4 let sit for an hour for soda to freebase the bufotenin agitating occassionally, then dry at low temp in oven

5 powder the result and pull with acetone and pour off into filter, repeat pulls until acetone remains clear

6 combine extracts and pour through a loose stuffed cotton ball to obtain clear yellow acetone

7 add 10% citric acid acetone until theres no more precipitation

8 pour through filter to collect alkaloid citrate

9 agitate over a long period of time until there is no acetone smell

10 time to freebase again, add enough water to dissolve the bufo citrate (50ml) then add 1g of sodium carbonate powder directly to the solution

11 flatten the caramel coloured freebase bufotenine whilst adding an excess of water to allow the sodium carbonate to precipitate all bufo

12 allow reaction to continue to completion, then pour off the water and dry out the bufotenine/alkaloids

13 dissolve the yielded impure bufotenine in a small quantity of boiling limonene. not all should dissolve, just the bufo and not the other alks

14 allow this solution to boil for 5 minutes then remove from boil. after 5 seconds of not boiling pour out, this will allow the non solutes to sediment but the bufo will crash out nearly instantly (within a minute) so needs to be done precisely

15 wait further until all the bufo has precipitated from the limonene then pour off. crush the resulting purer bufotenin and allow to evap any residual limonene

16 once there is no more trace of limonene, enjoy

 

[_Trip_]

This thread might be a good start:

2020 Bufotenine Extraction TEK + Analytical Data - Bufotenine and 5-MeO-DMT - Welcome to the DMT-Nexus

 

[h3allth]

This thread might be a good start:

2020 Bufotenine Extraction TEK + Analytical Data - Bufotenine and 5-MeO-DMT - Welcome to the DMT-Nexus

I'd love to follow this properly but I don't have any lab sort of equipment. I'm also very opposed to using naptha. The tek I gathered is for what materials I have available

 

[_Trip_]

I'm unsure limonene will have the same properties as boiling xylene does with bufo. Worth a try and you can report back (someone may have already tried, i haven't come across it yet though).

You wouldn't need any lab equipment for BW's tek. Why are ya worried about naphtha?
In addition with my limited runs a defat seems essential.

 

[h3allth]

I tried an LSA extraction crudely once when young, high and dumber. Managed to have a bad exposure to naptha fumes which lead me to much preferring less risky solvents.

Wouldn't the limonene sort of recrystallisation defat it as it wouldn't absorb the other alks?

Freebase Bufotenine Solubility
Acetone @ 20 C: soluble (5 g/100 ml)
Chloroform @ 20 C: soluble
Dichloromethane @ 20 C: soluble
Dimethyl sulfoxide (DMSO) @ 20 C: soluble (6 g/100 ml)
D-Limonene (Orange Oil) @ 20 C: insoluble
D-Limonene (Orange Oil) @ 176 C: soluble (more than 1.7 g/100 ml)
Ethanol @ 20 C: soluble
Ether @ 20 C: soluble
Ethyl acetate @ 20 C: soluble
Heptane @ 20 C: insoluble
Heptane with 40% MEK @ 20 C: soluble (0.53 g/100 ml)
Heptane with 50% MEK @ 20 C: soluble (1.22 g/100 ml)
IPA @ 20 C: soluble
MEK @ 20 C: soluble
Methanol @ 20 C: soluble
Naphtha @ 20 C: insoluble
Water @ 20 C: nearly insoluble in pure water (no acid or alkali added)
Xylene @ 20 C: nearly insoluble (less than 0.03 g/100 ml)
Xylene @ 144 C: soluble (1.5 g/100 ml)

Here this dude found that it is soluble in boiling limonene. I found someone talking about doing this, unusure if they said they had done it or talked about the theory of it and didn't keep track of sources for info.

I feel like I should hold off and acquire proper equipment like hotplate, stirrer, respirator etc to attempt this then I can follow the thread you've linked more thoroughly and confidently instead of try and throw something together crudely with kitchen utensils. I do have more seeds on the way so I can attempt up until the limonene confidently at least with this small sample. After that I'll wait for a respirator and hotplate to attempt the last steps and report if it was successful. Until then I'd have at least some more crude bufo/alkaloid extract to experiment with.

 

[_Trip_]

Good find, potentially could work then. I would guess frying the seeds like BW does is effective enough, unsure if there's much benefit baking them.

Respirator and goggles are a great idea. Check the details of your respirator most won't filter solvents. So I'd suggest you boil d-lemonene outside. You think naphtha is bad, i would imagine boiling d-lemonene wouldn't be much better.

 

[downwardsfromzero]

Respirator and goggles are a great idea. Check the details of your respirator most won't filter solvents. So I'd suggest you boil d-lemonene outside. You think naphtha is bad, i would imagine boiling d-lemonene wouldn't be much better.

h3allth, you would 100% need to do this with utmost care, maybe even using some kind of reflux arrangement (a condenser of the right type), and suitable heating via a hotplate or mantle. 176°C is getting in the range of a bit hot for comfort and you don't know how quickly (or slowly) the bufotenine will dissolve. And you've no guarantee that the boiling limonene wouldn't pick up the "other alkaloids" you've referred to. You might be better off playing with something like various blends of heptane and MEK if you're looking for crystallisation.

 

[h3allth]

Respirator and goggles are a great idea. Check the details of your respirator most won't filter solvents. So I'd suggest you boil d-lemonene outside. You think naphtha is bad, i would imagine boiling d-lemonene wouldn't be much better.

h3allth, you would 100% need to do this with utmost care, maybe even using some kind of reflux arrangement (a condenser of the right type), and suitable heating via a hotplate or mantle. 176°C is getting in the range of a bit hot for comfort and you don't know how quickly (or slowly) the bufotenine will dissolve. And you've no guarantee that the boiling limonene wouldn't pick up the "other alkaloids" you've referred to. You might be better off playing with something like various blends of heptane and MEK if you're looking for crystallisation.

Thank you for this. I've never heard of or seen this kind of equipment in any tek.

I definitely feel that for this sort of work proper chemistry basis is required which I don't have. A lot of these teks are aimed at people that have this I feel, yet describe things as though they are simpler than they actually are. A quick look over D-limonenes MSDS put me off boiling it without a respirator and suit on. Outside isnt really an option in an urban area, unfortunately.

I'll scrap my current extraction ideas and make a traditional preparaton for sublingual use like Dragon Rider has talked about in the right sub area. I'd love to follow the properly detailed extraction I was linked to by BW but I'll hold off for advice and the correct equipment until then.