psilocybin/ N-N DMT and Cancer! 😷

[Szeth Truthless]

Hello all,
this is my first post and I am happy to be here. I have been into other forums and understand basics and have done a lot of my own various projects over many years, many many moons ago. Life moves fast and can be quite random. As in to my hobbies as I was I was always on the responsible side.
Soo fast forward past all the aggressive exploration. Slowly fall out but I have started a family which hasn’t completely changed me but I am different also was diagnosed with a type of cancer and staged as 3. For 8 months before the diagnosis I knew something was wrong drs. Just wanted to monitor but I lost sleep worring about death. After a while I lost the worry’s not entirely but it’s natural.
I’m going thru chemotherapy and cannot work but I feel great most days and need hobbies or start my old ones I have been meditating a lot and I plan on being cured but.... A bummer if I’m holding out for cure and never get cured and never get to dive back in. Any thoughts my immune system is compromised (low WCBC) should that be an issue if I’m just like solo in my house with no one. Anyone have any experience with cancer and psilocybin or DMT?

Edited by Moderator. No discussion of buying/selling/sourcing.

 

[dreamer042]

Psilocybin has not been used directly in cancer treatment as such, but there have been multiple studies using psilocybin to address anxiety in late stage cancer patients. Here are just handful of references:

Grob, Charles S., et al. "Pilot study of psilocybin treatment for anxiety in patients with advanced-stage cancer." Archives of general psychiatry 68.1 (2011): 71-78.

Griffiths, Roland R., et al. "Psilocybin produces substantial and sustained decreases in depression and anxiety in patients with life-threatening cancer: A randomized double-blind trial." Journal of psychopharmacology 30.12 (2016): 1181-1197.

Ross, Stephen, et al. "Rapid and sustained symptom reduction following psilocybin treatment for anxiety and depression in patients with life-threatening cancer: a randomized controlled trial." Journal of psychopharmacology 30.12 (2016): 1165-1180.

Grob, Charles S., Anthony P. Bossis, and Roland R. Griffiths. "Use of the classic hallucinogen psilocybin for treatment of existential distress associated with cancer." Psychological aspects of cancer. Springer, Boston, MA, 2013. 291-308.

Nutt, David. "Psilocybin for anxiety and depression in cancer care? Lessons from the past and prospects for the future." (2016): 1163-1164.

Ayahuasca and harmalas also display anti-cancer properties. A few references on that:

Schenberg, Eduardo E. "Ayahuasca and cancer treatment." SAGE open medicine 1 (2013): 2050312113508389.

Topping, D. M. "Ayahuasca and cancer: a postscript." Bull Multidiscip Assoc Psychedelic Stud 9 (1999): 22-25.

Frecska, Ede, Petra Bokor, and Michael Winkelman. "The therapeutic potentials of ayahuasca: possible effects against various diseases of civilization." Frontiers in pharmacology 7 (2016): 35.

Khlifi, Daycem, et al. "Composition and anti-oxidant, anti-cancer and anti-inflammatory activities of Artemisia herba-alba, Ruta chalpensis L. and Peganum harmala L." Food and chemical toxicology 55 (2013): 202-208.

Lamchouri, F., et al. "In vitro cell-toxicity of Peganum harmala alkaloids on cancerous cell-lines." Fitoterapia 71.1 (2000): 50-54.

El Gendy, Mohamed AM, et al. "Harmaline and harmalol inhibit the carcinogen-activating enzyme CYP1A1 via transcriptional and posttranslational mechanisms." Food and chemical toxicology 50.2 (2012): 353-362.

These are just a very small glimpse of the abundance of research available on this topic, there are many hundreds of studies available regarding the (potential) role of psychedelics in cancer treatment, particularly in the case of harmalas/beta-carbolines. In short, to the question of whether it's safe to explore these compounds in the context of a cancer diagnosis, the data appears to support that it is. However, it's always wise to consult your physician regarding potential contraindications and interactions and to come up with a plan to integrate these alternative methodologies alongside the conventional courses of treatment.

 

[Szeth Truthless]

Thank you for your reply.
I have read a lot of those and about anxiety and I have also brought this up to
My Oncologist he always has a positive attitude says that’s for people who aren’t getting better you will be better and never really says not to. But he explains it really has no help in my treatment and usually for Terminal patients. So I suppose if it’s for terminal Patients it probably doesn’t effect chemo treatments. I was kinda maybe lookin for someone with personal experience. Either way il probably wait. Even now I feel I have a different perspective and appreciation for the people in my life. And little to no anxiety about death. But your response is much appreciated. I was prescribed cannabis with my chemo treatment plan. I am no stranger to cannabis and I try to break the stigma as I used to
Hide it well. I openly talk about using cannabis and I find a lot of medical cannabis patients don’t even like to talk about cannabis. But people always discuss getting drinks at work with their supervisor. So maybe you See my point on these substances maybe many people on cancer have used mushrooms but maybe will never share the experience from a fear of judgment. But again thanks for providing all those links.

 

[dreamer042]

Yeah, psilocybin hasn't really been researched in treatment of cancer, just for depression/anxiety, though the mind is a powerful thing and a little expanded perspective can go a long way in assisting self-healing.

Ayahausca/Syrian Rue/Harmalas have been used in the treatment of many types of cancers, I don't know your specific condition so I just chose some generalized papers, but if you research them in the context of your specific diagnosis you may find some interesting protocols to at least discuss with your docs.

Have you considers the non-psychoactive mushrooms? Things like Reishi, Chaga, and Turkey Tail? I haven't delved too deeply into the literature on them in the context of cancer treatment, but have heard some interesting offhand comments and anecdotes along the lines of them being effective, might be another line of exploration worth looking into.

Another tryptamine with a pile of of data in various forms of cancer treatment is melatonin. Most doctors are fairly misinformed about it in this context so don't expect too much from your oncologist if you bring it up, but if you head over to google scholar, the body of literature is quite substantial and worthy of exploration.

Just some ideas to consider. It sounds like you are already on a good track toward health and well-being. Let us know how it goes and if you encounter any interesting tidbits along the way.