i know it's cliche, but I sort of liken agents like bufotenine and dimethyltryptamine to a glimpse into schizophrenia...genuine hallucinations, seeing things that really aren't there. so yeah... who's to say those beings a schizo sees aren't real? if one thinks what one sees and experiences on DMT is reality, but denounces the reality of a schizotypal person, one is hypocritical.
agree i try to make this point often to people. is one type of hallucination more real then another?? is the visions of datura any less or more real then those of spice? yes the parts of the brain being effected are different and hence a different experience but what classifies a substance's experience as more real then another substances experience?