for full on breakthroughs i prefer achuma
prepared by fileting the outter 5mm green flesh (no skin or spines) drying this flesh, then powdering it. making a resin by evaporating the tea made from the rest of the cactus not fileted (minus the waxy flesh). mix the powder with the resin to make marbles and eat those marbles at sundown after fasting all day + hydrating. 2 feet is the magic amount to go beyond, more than that and its unnecessarily powerful, less than that and i tend to not leave linear reality as cleanly or completely
i also like using changa/dmt while on cactus/mescaline for instant peaks, i find that if im not using an entheogenic dose i like to hit that level with dmt/changa
mescaline is great, better than any drug you could buy IMHO, however i do not prefer to use it for breakthroughs, rather for empathogenic/therapeutic/ recreational use. it has a different feel to it. if i decide to concentrate the entire cactus for breakthrouhgs id do an ethanol resin, id also feel comfortable dosing the resin like extracted mescaline, it to me has qualities of both unadulterated cactus and mescaline salt
i like combing lsa with cactus/mescaline it gives the experience more euphoria and visual texturing (much like adding psychotria to a caapi brew)
calea zacatechichi goes well with all entheogens and is amazing by itself, i take it almost nightly in conjunction with either melatonin or harmalas
i used to smoke weed during my cactus experiences, i was careful to only smoke after the peak diminished as to not get an avalanche of paranoia but i found i felt safer dosing higher without it, and had more profound experiences instead of trivial intensity
im not the biggest dmt user, infact i much prefer cactus than dmt, i dont entirely enjoy leaving myself while using dmt, for me its often riddled with trepidation. i find that blasting dmt on cactus though is a much smoother transition to hyperspace as youre already in the entheogenic mindset. ive willingly gone as far and farther with achuma than i have with accidental heroic dosing of mushrooms and aya, smoking dmt has never gotten me to the level that the oral entheogens have.