Yes, I have given this much thought - though I haven't taken a spice trip yet, I've read many a trip report and experienced something akin to cosmic machinery on a breakthrough salvia trip - though it is surely a different beast.
We have "laws" of nature. They hold up under almost any scrutiny. We know that gravity will continue to behave as it does. The laws of thermodynamics do not fail in our "window" of the universe. They may very well be totally universal.
The laws of thermodynamics are a pretty recent discovery. They were discovered, in fact, in the industrial revolution - specifically as it became more crucial for mankind to build great machines to work for them. In an attempt to maximize machine efficiency, experiments were done and thermodynamic laws were discovered, which seemed to underly everything.
1. Energy or matter can neither be created nor destroyed. It is only changed and exchanged.
2. Energy exhibits entropy. No system can be 100% efficient - There is always some energy "vented" in a mechanical process.
3. There is a temperature "bottom" of absolute zero where entropy ceases. The law suggests it is impossible to actually achieve this temperature.
We don't know why the universal laws are what they are, but we do know that they seem to be crucial in order for our earthly existence. If the laws of physics and thermodynamics were even slightly different, we could never have evolved in the universe.
DMT, for many people, reveals a cosmic machinery that actually appears to be regulated and maintained by entities. Nobody knows the nature of these things. In medieval times it was believed that the sky was a crystal sphere which spun around the flat earth. But how did it spin? What force caused its perpetual movement? Science of the day could not answer this, and so the temporary solution was to blame the angels - heavenly workers on the 'other side' of the crystal sphere whose "job" was to spin the cosmos around the earth.
Sounds like a terribly tedious task to me. I sometimes wonder - what if the grind doesn't cease after death? If awareness does in fact constitute energy, and that energy is part of the mechanical spinning and changing of the universe, then we very well may all be destined to be cogs in a machine for the duration of the universe. Which means that life in this day and age is perfectly suited for getting us very much used to this fate!
Perhaps the machinery on display during a DMT trip is a way for our minds to cope with a visionary journey into bewilderingly complex 'natural' machinery - either into the brain itself - the neural cogs that form the patterns of our minds - or into the "vast machinery of nature" itself as Carl Sagan put it.