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Science paper Traditional Therapeutic Uses Of Peganum harmala L. By Local Populations In Province of Sidi-Bel-Abbes

Pure science papers to share and discuss.
Traditional Therapeutic Uses Of Peganum harmala L. By Local Populations In Province of Sidi-Bel-Abbes (Western Algeria). Oct. 2024
https://www.researchgate.net/public...In_Province_of_Sidi-Bel-Abbes_Western_Algeria

I find a few things intriguing. One it a that the seeds seems to be used by pregnant women and another is a method of 'steam-cooking'. "They explain that this method of preparation reduces the toxicity of the seeds without any risk of poisoning.".
 
It would be neat to have a thread dedicated to all of the scientific and non scientific literature on Syrian rue available.

I know there are at least two books published on it one of which a beloved member sent me which unfortunately I have yet to read.

Thanks for this link, I hadn't come across this one yet.

I love sending this one to friends and family who might be drawn to work with this amazing plant.

 
So, P. harmala seed apparently contains anthraquinones. It would be best to look into this claim a little more, but that's one good reason to be wary of chronic toxicity with whole rue ingestion.
Well, I did look a bit further - the anthraquinones were only identified via presumptive testing, not to mention the colour change for this was suspiciously similar to that obtained with 'harmala red'. If anything, the quantities were low and the concentration was below the limit of detection of their quantitation method. [Edit: or maybe they didn't have a quantitation method - "n.d." is a bit vague...]

3. Results Harmel grain A

Preliminary phytochemical screening in the leaves of P. harmala
showed the presence of flavonoids, alkaloids, saponins, tannins,
glycosides, terpenoids and steroids and the absence of anthraquinons,
whereas the results in the seeds showed the absence of flavonoids
and the presence of alkaloids, saponins, tannins, glycosides,
anthraquinons, terpenoids and steroids. Quantitative analysis from
this study showed that the seeds of P. harmala contained high
levels of alkaloids with low quantity in leaves, whereas the leaves
contained the highest levels of flavonoids (Table 1).

Table 1 - Phytochemicals screening of seeds and leaves of P. harmala.
Concentration(mg/g)
Extract constituentsseedsleavesseedsleaves

Flavonoids
Alkaloids
Glycosides
Tannins
Saponins
Steroids and terpenoids
Quinons
Anthraquinons

-
+++
+
+++
++
+
++
+

+++
+
++
+++
++
+
-
-

1
5
35
13
nd
nd
nd
nd

nd
nd
nd
nd
nd
nd
nd
nd
-: Absent; +: Present; +++: Present in high quantity; nd: Not determined.
 
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