To be clear when I said a short period I did not mean weeks or months, I meant over a decade or so. Which is a short period over a lifetime. I feel this pertains to dementia as it is a disease that happens later in life, over a long lifetime. So it is obviously accumulative. It is a disease that has many contributing factors. First generation antihistamines are being studied as one of those factors. There are quite a few other studies on this now other than the one you quoted.
Indeed I was likely thinking of that study as it states they followed participants medication use over a 10 year period (Which is maybe why I had a decade in my mind). Interesting to note, iirc, such drugs are know to increase dementia symptoms in people with dementia.
I never said it wasn't safe nor that it is relevant to only cyproheptadine as you stated? I clearly said first generation antihistamines i did not single it out. I also didn't say it causes, I said is linked to. If im being honest your post reads like a chat gpt reply.
I also do not see a study passing ethics balances and checks if they were to say give first generation antihistamines to a group of 20 year olds everyday for 10 years to see if it induces early onset dementia. That is to say it would be hard scientifically gauge the damage long term use could do over a long period in a large sample group of young healthy people, especially as many users of all ages use such medications as regular sleep aids.
I would therefore respectfully argue what I wrote is accurate. In addition, I think it is good that people have access to information on potential risks no mater how big or small to mitigate risk and make their own informed decisions regardless of the drug. I hope by pointing this link out people can be mindful.
PS. I have editing my post to read "extended period" to better reflect what I meant. Thank you for pointing this out.
