mikeAtHome
The only God I can imagine is a God that I can't p
Hi everyone. I’m planning my first extraction (in the DMT world) using MHRB and have been reading threads, searching our Wiki and slugging through a ton of research done on plant-based extractions in general as well as those targeting alkaloids. I’ve done a number of extractions before but on compounds very different from DMT. For one thing, the end product extraction (as opposed to intermediate extractions for isolating impurities etc.) always used NaOH/HCL. Nice strong conjugates. Additionally, my end product was a salt. So: no need for smelly solvent evaps or multiple precips, stable, easily washed (cold acetone) and Xtalised (boiling IPA). I really want to go the FASx way. My questions are:
1. If I’m reading things correctly. DMT-f is VS in H2O (1g/ml). My previous extractions were usually pulling 1 to 2 grams of honey with identical solubility. But I used about 75ml in the aqueous layer and usually had very little come out on the 3rd pull. It really didn’t matter what the volume of basified solvent was. Other folks going after an oz. of product would report 14g from their first 100ml pull! Can someone explain how DMT is different? I read in one thread someone saying that DMT was stubborn about coming out of water but that was in reference to the extraction from bark. And I could swear I'm heard other members say it wasn't that water soluble at all (I know the acid sure isn't). Is it really that stubborn in a titration or am I using incorrect solubility data?
2. I would also like some advice on which of 2 ways I should go when it comes to obtaining the salt. One way is to follow FASx extraction guidelines and go right to the DMT Fumarate. Another way would be to follow some other tek – I like STB and Jorkest’s tek looks like it got good yields. That tek uses NaOH which is not compatible with FASx. Not a problem. I could use HCL to obtain the salt. Maybe give it a wash and then basify with Ca(OH)2 and salt out using fumaric acid, wash w. cold acetone and Xtalize w. boiling IPA (soluble at 1g/200ml). Will this work or is it just plain crazy?
This is a much different world than I am used to and I’m obviously no chemist so please don’t take this as a challenge to tek being used in FASx and A/B but… A lot of the tek is more volume-oriented than it is ph-oriented when it comes to hitting certain targets. Maybe I’m just paranoid but I’d always check ph prior to water washing a basified solvent and after every water pull to make sure I was on target (ph=6.5) . You’re using different A/B combos here and I know each pairing can have its own rules about the ease or lack thereof in changing ph. And I really don't completely understand all of the ionic influences in play. It would be nice to not feel so anal about ph if there’s no call. It’s a PITA and I go through a shit-ton of ph paper.
Probably took too long to ask a couple questions; will attempt more brevity from here on… Thanks.
1. If I’m reading things correctly. DMT-f is VS in H2O (1g/ml). My previous extractions were usually pulling 1 to 2 grams of honey with identical solubility. But I used about 75ml in the aqueous layer and usually had very little come out on the 3rd pull. It really didn’t matter what the volume of basified solvent was. Other folks going after an oz. of product would report 14g from their first 100ml pull! Can someone explain how DMT is different? I read in one thread someone saying that DMT was stubborn about coming out of water but that was in reference to the extraction from bark. And I could swear I'm heard other members say it wasn't that water soluble at all (I know the acid sure isn't). Is it really that stubborn in a titration or am I using incorrect solubility data?
2. I would also like some advice on which of 2 ways I should go when it comes to obtaining the salt. One way is to follow FASx extraction guidelines and go right to the DMT Fumarate. Another way would be to follow some other tek – I like STB and Jorkest’s tek looks like it got good yields. That tek uses NaOH which is not compatible with FASx. Not a problem. I could use HCL to obtain the salt. Maybe give it a wash and then basify with Ca(OH)2 and salt out using fumaric acid, wash w. cold acetone and Xtalize w. boiling IPA (soluble at 1g/200ml). Will this work or is it just plain crazy?
This is a much different world than I am used to and I’m obviously no chemist so please don’t take this as a challenge to tek being used in FASx and A/B but… A lot of the tek is more volume-oriented than it is ph-oriented when it comes to hitting certain targets. Maybe I’m just paranoid but I’d always check ph prior to water washing a basified solvent and after every water pull to make sure I was on target (ph=6.5) . You’re using different A/B combos here and I know each pairing can have its own rules about the ease or lack thereof in changing ph. And I really don't completely understand all of the ionic influences in play. It would be nice to not feel so anal about ph if there’s no call. It’s a PITA and I go through a shit-ton of ph paper.
Probably took too long to ask a couple questions; will attempt more brevity from here on… Thanks.