UgraKarma
Esteemed member
For some time now, I've come to consider 5-MeO-DMT a major no-no, rife with contraindications, when used in tandem with harmalas, or MAOIs. Because 5-MeO is so physical, and seems to share tactile qualities with phenthylamines which also have harsh reactions when combined with MAOI's, this seemed to make perfect sense to me and I didn't dig into it much further.
On a very old thread, 69ron comments on the efficacy of 5-MeO-DMT and harmalas taken sublingually, and it has piqued my interest. As far as I can tell, there's no guide for dosing, as one might easily find Googling for heroic dose/psilohuasca, ayahuasca, pharmahuasca, etc... If anyone is able to come up with a working dosage scale, or even share odds and ends notes on their subjective experience, I'd be interested in reading about the experience, and how the signature of the rue imprints itself onto the 5-MeO experience, (i.e. if you found MAOIs to enhance the low-dose empathogenic/entactogenic effects, and if its synergies could be considered desirable all the way through to the "release dose".)
A few notes on where I'm coming from:
I have about 30-60mgs (eyeballed) of HCL 5-MeO, which would be much better for sublingual administration than the larger amount of freebase I have, however I'm without freebase harmalas at the moment. Would you consider this experience warrant the trouble of running a rue extract? I enjoy low-dose intranasal administration for the HCL, so if it's not a tremendous difference experientially, I'll probably not rush to try this combo before the end of the year, and simply continue to use it in this fashion.
On a very old thread, 69ron comments on the efficacy of 5-MeO-DMT and harmalas taken sublingually, and it has piqued my interest. As far as I can tell, there's no guide for dosing, as one might easily find Googling for heroic dose/psilohuasca, ayahuasca, pharmahuasca, etc... If anyone is able to come up with a working dosage scale, or even share odds and ends notes on their subjective experience, I'd be interested in reading about the experience, and how the signature of the rue imprints itself onto the 5-MeO experience, (i.e. if you found MAOIs to enhance the low-dose empathogenic/entactogenic effects, and if its synergies could be considered desirable all the way through to the "release dose".)
A few notes on where I'm coming from:
I have about 30-60mgs (eyeballed) of HCL 5-MeO, which would be much better for sublingual administration than the larger amount of freebase I have, however I'm without freebase harmalas at the moment. Would you consider this experience warrant the trouble of running a rue extract? I enjoy low-dose intranasal administration for the HCL, so if it's not a tremendous difference experientially, I'll probably not rush to try this combo before the end of the year, and simply continue to use it in this fashion.