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Publication Anti-inflammatory effects of psychedelics
- Thread starter Traged
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This is great, I was talking with my friends about exactly this just a couple of days ago!
I wonder how much a person needs to take once something like MS has progressed to the point where people are already taking biologics/antibodies?
Personally my experience is that it does work to some extent(not for MS but other auto immune inflammation).
Still even after years of tripping balls on DMT, ayahuasca, psilocybin, LSD…microdosing…I ate Iboga.. still I ended up needing potent pharma drugs.
My TNF-a levels have tested pretty damn high while deep into microdosing so I would be interested in what it looks like in the days after a full trip.
Sometimes tryptamines help but not so much if I’m already in a flair so bad I need pharma drugs. I find personally I need my prescription for a few days until I’m okay and then I can use psychedelics, herbs and my diet carefully to maintain.
Personally my experience is that it does work to some extent(not for MS but other auto immune inflammation).
Still even after years of tripping balls on DMT, ayahuasca, psilocybin, LSD…microdosing…I ate Iboga.. still I ended up needing potent pharma drugs.
My TNF-a levels have tested pretty damn high while deep into microdosing so I would be interested in what it looks like in the days after a full trip.
Sometimes tryptamines help but not so much if I’m already in a flair so bad I need pharma drugs. I find personally I need my prescription for a few days until I’m okay and then I can use psychedelics, herbs and my diet carefully to maintain.
Wow I really need to get back to mushrooms.
Also forgot to add that the most relief I got from my symptoms was from eating Iboga. The experience itself was somewhat rough physically but it did provide 2-3 weeks where my immune system really did calm down and I felt at peace.
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I've found that DMT and changa have similar effects on certain types of pain. It helps a lot with my torn labrum and spinal issues. I can always use more reasons 
One love
One love
I acquired a rare complicated skin issue when my immune system over-reacted to a pharmaceutical medicine 4 or 5 years ago, and it's very visually obvious to me that inflammation is down after a deep psychedelic session. Interestingly it seems that the reduction in inflammation is directly correlated with the depth/coherence of the experience, not just the dose. No idea how that works, but I can take the same dose of LSD/DMT, not get as deep for whatever reasons, and it will be noticeably less effective.
I notice some reduction in the moment but the most seems to be the day after a session.
I notice some reduction in the moment but the most seems to be the day after a session.
Will look into the paper!
I've just recently found some of this information on the web, really fascinating and quite relevant. I hope this research gets developed further.
Recetnly, after doing a few conservative doses of psilohuasca with foraged Psilocybe semilanceata and harmala hcl I've found that some of the inflammation has reduced altough only for a short while, however still pleasant and useful.
I've just recently found some of this information on the web, really fascinating and quite relevant. I hope this research gets developed further.
Recetnly, after doing a few conservative doses of psilohuasca with foraged Psilocybe semilanceata and harmala hcl I've found that some of the inflammation has reduced altough only for a short while, however still pleasant and useful.
Yes, I've had the same experience recently with psilohuasca.
It might be interesting to mix psilocybe mushrooms with other medicinal mushrooms such as lion's mane or reishi and others. I also wonder how different psilocybe mushrooms might work in this regard, for example various different woodlovers or liberty caps and others.
One's whole lifestyle can be geared toward anti-inflammatory gains. From the type of food we eat, to the exercise we do, to the proper sleep we get, to the daily earthing we do, to the cold water immersions... Psychedelics cannot be the main source of anti-inflammatory gains in one's life, but one source among many, and mostly likely the synergistic effect of all these practices combined is stronger than the sum of the parts. IMO.
Something as simple as walking barefoot on the earth (or a bit not so simple as sleeping on properly grounded beds/sheets) has a dramatic effect on inflammation levels. The studies are there, you can look them up.
Something as simple as walking barefoot on the earth (or a bit not so simple as sleeping on properly grounded beds/sheets) has a dramatic effect on inflammation levels. The studies are there, you can look them up.
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I had a time when I slept on a thin mat directly on the earth. I recognized an unusual well being during that period.
There are commercial grounding bedsheets that hook up to the ground line in houses. İf the line is good quality and does not have any stray charge, theoretically it should work. You can also hook up the sheet directly in the earth with a long conductive metal rod going deep in the earth.
There are commercial grounding bedsheets that hook up to the ground line in houses. İf the line is good quality and does not have any stray charge, theoretically it should work. You can also hook up the sheet directly in the earth with a long conductive metal rod going deep in the earth.
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I think how I really feel about this is that psychedelics are not going to be a real cure for chronic inflammation due to auto immune diseases. I see often people throwing around words like “ anti inflammatory” and it’s not so specific. Like so far I haven’t found a psychedelic that blocks all of the interleukins I need to block for ankylosing spondylitis. Mescaline actually seems to put my disease into overdrive.
I wish more people with serious diseases had stories to tell like “ I took shrooms and now my lupus is in remission and I’m off the meds that cost 20 grand” but those stories are nearly non existent. Mostly it’s people with low grade inflammation and not dealing with serious or life threatening levels of inflammation that feel they can just eat a mushroom cap or ground to feel better.
I know that psychedelics help me but I also can’t help but roll my eyes at some of it because I feel that they do not really deal with that level of inflammation very well and I feel like most people don’t understand what that type of chronic inflammation is like to experience and just lump everything as “inflammation” which is very problematic. Auto immune diseases are on the rise and it’s become trendy to suggest anything slightly anti inflammatory is going to be a treatment.
I wish more people with serious diseases had stories to tell like “ I took shrooms and now my lupus is in remission and I’m off the meds that cost 20 grand” but those stories are nearly non existent. Mostly it’s people with low grade inflammation and not dealing with serious or life threatening levels of inflammation that feel they can just eat a mushroom cap or ground to feel better.
I know that psychedelics help me but I also can’t help but roll my eyes at some of it because I feel that they do not really deal with that level of inflammation very well and I feel like most people don’t understand what that type of chronic inflammation is like to experience and just lump everything as “inflammation” which is very problematic. Auto immune diseases are on the rise and it’s become trendy to suggest anything slightly anti inflammatory is going to be a treatment.
I agree. And obviously everyone's mileage may vary depending on loads of factors. It seems to help me with the most inflammed area temporarily, but is far from a cure and low doses seem to have minimal effect.
I think there is a lot of untilled healing potential of psychedelic-related states, but to what degree and how practical is it at the moment is a complicated question
I think there is a lot of untilled healing potential of psychedelic-related states, but to what degree and how practical is it at the moment is a complicated question
Here, I'm of the same opinion. Healing depends on how coherent and balancing the experience is. I feel that when we tap into hidden resources of our bodies, it gives the strongest effect. A heavenly session where you align with the Cosmos and Nature would produce a real boost in life's energy. On the other side, a horrific scary experience could leave you in a worse condition than when you started. I feel that's the power of traditional Amazonian shamanism. They work on our mental body, and the flesh adapts in the days after.
Amazonian curranderos are on a level beyond any western herbalists. It’s hard to compare that to just psychedelics or even healing with ayahuasca etc… they put people on intense diets…purge them and give them powerful herbs for extended periods and have invisible doctors to help. It’s way beyond any one thing and that’s probly why people find healing.
I agree with your statements.
How I see the anti-inflammatory topic is that this is only the very beginning of some potentially serious research into the topic. When these compounds will be studied in detail in this regard it is possible to develop various analogs and protocols that will specifically target the inflammatory pathways. Psychoactivity may be lost along the way. I only see positive things with having another tool to work with.
There is a possibility that we do not consider enough of the psychosomatic causes for inflammation. (and all other ailments)
My mother does One Brain - three in one concepts. It is basically way to unblock and relieve stress - sometimes from prenatal parts of life, sometimes from childhood or other traumas. Lot of those things cause inflammation, or even other life threatening ailments.
I think that we are only scratching surface here. And even bigger relieves would be possible, with higher and repeated doses. Rewiring pathways that cause inflammation without reason or with reasons that they are not supposed to. Studies wont be there, though, because we are going in territory that sane scientist would not go even if he thought it would be possible.
It is placebo, at least partial. The same way our medicine works many times. The information and belief that it is gonna help, will improve efficacy. Hell, it would work, and works on occasions even without real medicine.
If you believe your doctor and he tells you it is not curable. I have bad news for you. You either stop believing him or you will be his believer, I mean patient.
It is weird headspace, this thing. We just might me be makers of all of our problems... (in some way)
My mother does One Brain - three in one concepts. It is basically way to unblock and relieve stress - sometimes from prenatal parts of life, sometimes from childhood or other traumas. Lot of those things cause inflammation, or even other life threatening ailments.
I think that we are only scratching surface here. And even bigger relieves would be possible, with higher and repeated doses. Rewiring pathways that cause inflammation without reason or with reasons that they are not supposed to. Studies wont be there, though, because we are going in territory that sane scientist would not go even if he thought it would be possible.
It is placebo, at least partial. The same way our medicine works many times. The information and belief that it is gonna help, will improve efficacy. Hell, it would work, and works on occasions even without real medicine.
If you believe your doctor and he tells you it is not curable. I have bad news for you. You either stop believing him or you will be his believer, I mean patient.
It is weird headspace, this thing. We just might me be makers of all of our problems... (in some way)
That's what I implied in my reply about Amazonian healers, and @Jamie01 added that it's much more than that, involving a more holistic approach to healing with many methods.
Sure, your belief in a positive result plays a big role, but it goes beyond that. I feel even a total unbeliever could receive healing within the Amazonian system. Ayahuasca is just one of thousands of plants they use, and it's primarily for diagnosis. They shift energy with tobacco and heal with certain plants we've never heard about.
We can't see past our cultural myopia, and that puts the brakes on what is possible. Why do you think terminal patients sometimes recover? Is it their faith in the process? Most of them fully lose faith at that point and remain completely open to life. If they encounter a real healer in that state, a genuine revival becomes a possibility. Life's more mysterious than we think
