Psychedelics and the Human Receptorome 2024-06-08

[The Traveler]

The Traveler submitted a new resource:

Psychedelics and the Human Receptorome - This manuscript is a reference work on the receptor affinity pharmacology of psychedelic drugs.

Abstract

We currently understand the mental effects of psychedelics to be caused by agonism or partial agonism of 5-HT2A (andpossibly 5-HT2C) receptors, and we understand that psychedelic drugs, especially phenylalkylamines, are fairly selective forthese two receptors. This manuscript is a reference work on the receptor affinity pharmacology of psychedelic drugs. Newdata is presented on the affinity of twenty-five psychedelic drugs at fifty-one receptors, transporters, and ion...

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