Pumpy
Titanium Teammate
Neurological underpinnings of habit and desire! Or attachment.
Glutamate homeostasis is a very interesting topic!
Author: To explore the physiological mechanisms
residing in prefrontal projections into the ventral stria-
tum (nucleus accumbens (NAc) that could constitute
the pathological impairments in the ability to control
drug-seeking behaviour.
Many animal models of addiction are currently used to study drug-induced changes in
brain chemistry, physiology and behaviour. These models can be grouped into two
subcategories: those that use a non-contingent, experimenter-delivered drug, and
those that use a contingent, self-administered drug. Given that human addiction
involves drug self-administration, the face validity of the latter models exceeds that of
the former. However, non-contingent models are still used because of the relative ease
of drug delivery and because of overlap in some of the biological changes elicited by
contingent and non-contingent drug administration
Glutamate homeostasis is a very interesting topic!
Author: To explore the physiological mechanisms
residing in prefrontal projections into the ventral stria-
tum (nucleus accumbens (NAc) that could constitute
the pathological impairments in the ability to control
drug-seeking behaviour.
Many animal models of addiction are currently used to study drug-induced changes in
brain chemistry, physiology and behaviour. These models can be grouped into two
subcategories: those that use a non-contingent, experimenter-delivered drug, and
those that use a contingent, self-administered drug. Given that human addiction
involves drug self-administration, the face validity of the latter models exceeds that of
the former. However, non-contingent models are still used because of the relative ease
of drug delivery and because of overlap in some of the biological changes elicited by
contingent and non-contingent drug administration
