Are Lophophora williamsii var. Caespitosa active\ contain mescaline

[Hatter]

I have the opportunity to obtain a beautiful Lophophora williamsii var. Caespitosa and was wondering if these have a good mesc alk profile? Anyone with experience please chime in and help. Thanks

 

[espurrr]

yes, and also one of the fastest growing / pupping varieties of peyote, answers are an easy google search away tho

 

[Hatter]

Thanks I kept finding contradicting info

 

[LysergicAbreaction]

Technically, "ceaspitose" is a "growth form" rather than a "variety" and can be exhibited by several of the lophophora species, so I am uncertain that the cacti being ceaspitose is any type of indicator of potential mescaline content.

I have had a Caespitose lophophora williamsii cluster for about 7 years now. Its a great cacti to grow in my opinion, it does grow a decent amount (for a lophophora) every season, and has been more than easy to care for.

I do not have any intention of consuming this cactus, so I have never really considered mescaline content, but I did manage to dig up some related information:

Multiple headed growth often results following decapitation and is also the norm in grafted plants but caespitose individuals can be found in almost any intact healthy peyote population. They are capable of forming large mounds, up to a meter across according to Anderson, that are commonly referred to as “planchas“.

There is something that is present in horticulture which does not always require decapitation for multiple pupping but they are often propagated through grafting. There are multiple forms of these “caespitosa” in horticulture so care should be taken not to automatically equate them with each other without adequate additional information. It is also not to confuse these with the pupping induced by grafting.

A large crown surrounded by smaller ones is common but one clone in particular offsets vigorously with many small 5-ribbed crowns that stay fairly small and has a form that suggests it may be some type of a densely clustering semi-monstrose (the pupping reminds me somewhat of that of Mammillaria bocasana cv. Fred).

There are an unclear number of horticultural offerings but it is clear there are at least several that are distinct from each other. What has been tested by Habermann and by Štarha and by Fujita were all horticultural and they do not all appear to have been the same plants despite bearing the same name. Štarha and Habermann may have tested the same offering but it appears Fujita did not as his plant was found not to contain mescaline. Fujita included a photograph but Štarha and Habermann did not unless it was in a paper that I have not yet accessed.


Reported analysis of Lophophora williamsii f. caespitosa Y.Ito n.n.


Mescaline 0.701% (± 0.085) [dry wt?]

Pellotine 0.300% (± 0.095)[dry wt?]

Habermann 1978a (from Štarha in Grym 1997)]

Pellotine (Major) Habermann 1978a (From Štarha n.d.); Anderson 1980 cited Habermann 1977 & Habermann 1978a; [1.819% (± 0.212) (from Štarha 1997 citing Habermann 1978a)]; (65.2% & 65.5% of total alkaloid* [Štarha 1997 cited Štarha & Kuchyňa 1996])

Another analysis of a plant bearing this name was published (in Japanese) by Fujita et al. 1972. [Note 25]

They reported four new alkaloids (and five familiar ones):

1,2-Dimethyl-6,7-dimethoxy-8-hydroxy-3,4-dihydroisoquinolinium inner salt (0.00008% fresh wt.)

2-Methyl-6,7-dimethoxy-8-hydroxy-3,4-dihydroisoquinolinium inner salt (0.001% fresh weight)

1-Methyl-6,7-dimethoxy-8-hydroxy-3,4-dihydroisoquinoline (0.0001% fresh weight)

6,7-dimethoxy-8-hydroxy-3,4-dihydroisoquinoline (0.0008% fresh weight)

Pellotine (0.01%)

Anhalidine (0.005%)

Anhalonidine (0.001%)

Anhalamine (detected)

Lophophorine (detected) [Note 26]

All % by fresh wt. They did not detect mescaline suggesting this caespitosa might be derived from another Lophophora species.
Fujita analyzed plants grown in Japan.
They unfortunately assigned the previously used name Peyotine to one of their new molecules!

This was only partially translated from the Japanese (through the kind help of J.Hanna and friends).

They were using Cereus pitajaya DC. as the stock for the graft photographed. They also listed the names Cereus pruinosus Otto and Cereus tortuosus Forbes in the text. I assume in reference to other common choices of preferred grafting stock?

The translator believed the grafted plants were not used in the analysis which begs the question as to why grafted plants were shown with apparent grafting stock choices seemingly being discussed.

Lophophora williamsii "caespitosa" – Trout's Notes

sacredcacti.com

If it's a lophophora williamsii, it should contain mescaline, however, one must also consider that mescaline production is also influenced by a series of outside factors, such as certain environmental influences, the genetics of your particular cacti, and so on. There are methods that are supposed to increase mescaline content, such as mild stressing of the cactus, the theory being that mescaline is produced in the cacti as a response to stress, similar to how humans produce cortisol when stressed. Other options include feeding the plant 3,4-dihydroxy-phenethylamine or other precursor compounds for the plant to metabolize into the desired mescaline end product. I am not sure how well any of these methods work, but the information has been out there for quite a while, so I'm sure someone could personally give you their opinion if you asked around.