alladinsgrandpa
Rising Star
My apologies.
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Autism = high production of DMT in pineal gland?
- Thread starter sonofsnow
- Start date
SWIM just came to remember from some "bad" trips on mushrooms back in the days. That he was told that B12-vitamins and sugar would help to get the trip finish faster. SWIM tried this some times and it seemd to help, maybe placebo. But if it works in wich way does it work?
And would it work on a DMT trip as well?
Tnx for bringing it back to topic folks:d
Best of wishes
And would it work on a DMT trip as well?
Tnx for bringing it back to topic folks:d
Best of wishes
VisualDistortion
Rising Star
Alright, I'll also say that it has been determined that it is unlikely that DMT is produced in the pineal gland. yes, Joe Rogan is mistaken.
Here is some information about autism that has actual REAL research to support it.
Here is some information about autism that has actual REAL research to support it.
VisualDistortion said:
Thanks for posting this VisualDistortion, do you know where the DMT production-Pineal Gland link has been shown to be unlikely (ie reference?).
Got some good insights from that article on research on autism, but as the author of the review of the Scientific American article pointed out, the researchers have some interesting findings, particularly with the Mirror Neuron results, but to suggest any sort of causal link with what they've is not justified. I find this bias in "scientific" articles frustrating - where researchers find parallels between experienced phenomena - autism disorder in this case - and brain or body hardware, and conclude there's a causal link. It's like studying the image on a television by looking at the parts on the TV, whereas in reality the signal that's passing through the TV hardware is just as responsible for the image on the screen.
I don't recall which journal it was in (benzyme could probably tell you), but no rna transcripts of INMT (indoleamine n-methyl transferase, an enzyme required for DMT production) occur in the pineal. Without INMT, it's just not very likely.
Endogenous Psychoactive Tryptamines Reconsidered - An Anxiolytic Role For Dimethyltryptamine (DMT) | PDF | Hallucinogen | Serotonin
Summary The presence of the potent hallucinogenic psychoactive chemical N,N-dimethyltryptamine (DMT) in the human body has puzzled scientists for decades. Endogenous DMT was investigated in the 1960s and 1970s and it was proposed that DMT was involved in psychosis and schizophrenia. This...
"A contemporary investigation, utilizing modern
genetic and structural techniques, has provided a
more detailed analysis of INMT, but does not provide
a complete story. In two studies, Thompson
et al. [35,36], cloned, expressed, localized, and
characterized the activities of rabbit and human
INMT. Using Northern blot analysis, they found rabbit
INMT transcripts expressed heavily in the lung,
moderately in the liver, and weakly in the brain. Human
INMT was expressed in the lung, thyroid, adrenal
gland, heart, muscle, and spinal cord, but not in
the brain. The authors observe high Km values (an
order of magnitude higher than in previous studies
[33,34]) of TYP for recombinant human INMT and
an absence of INMT mRNA transcripts in the brain.
Thus, Thompson et al. conclude that the production
of DMT in humans is not physiologically significant.
Their conclusion places much weight on the significance
of observed Km values for recombinant human
INMT and does not take into account several
additional genetic and enzymatic concerns."
autism probably has nothing to do with DMT, and melatonin isn't an MAOI. pinoline is.
