Benjamin_James said:
Nathanial.Dread said:
From a neuroscience standpoint, Ayahuasca that contains DMT is functionally almost identical to smoked DMT ... the neurological effects are largely the same.
This to me simply illustrates the point that neuroscience is severely limited in explaining what is going on during these experiences.
jamie said:
Given that we can account for the differences with measurable physiological changes to the body, talking about cosmic, spiritual stuff seems kind of pointless.
So... whereas before you said that they are "functionally almost identical", you're now saying that the differences can be measured physiologically? How do measurable physiological changes give us any insight into the experiential dimension? This is a DMT forum titled "First Steps in HYPERSPACE" right? Most of the time the "cosmic, spiritual stuff" is all we have to go on. As much as I would love for science to get on board with psychedelic experiences, I'm not so keen on being 30 years behind the curve, waiting for science to get a grip on this stuff.
I said they are
almost identical, and the discrepancies can be very effectively explained by a scientific analysis. The primary difference between smoked DMT and DMT consume orally, with an MAOI is that much more smoked DMT makes it to your brain (since it's not metabolized in the stomach, and the mucous membranes in the lungs are more permeable, so more gets into the bloodstream) and the smoked molecule makes to the brain much faster (lung tissues allows way more molecules/sec to cross).
And you can say that neuroscience is limiting, if that's your belief and I can respect that, however, neuroscience is really all that we've got. You can't empirically measure someone's subjective religious experiences (not yet anyway, I hope to change that one day

), or what's happening in their "soul" or "third eye" or whatever because, there's no valid scientific evidence that such things exist. You can however look at the action of DMT on 5-HT receptors in the brain and the functional effects that 5-HT receptor agonism has on blood flow in certain areas: all things that are very measurable.
You can even correlate receptor agonism and area activation with certain, broad, subjective experiences, however, you still have to tie it back to measurable actions in the brain for it to be meaningful and useful.
I'm not denying that Ayahuasca and DMT can be powerful, personal, spiritual tools, but given the highly individualized nature of the experiences, they are just that: personal. My experiences with mushrooms and DMT have been wonderful: they opened my eyes to new ways of thinking and lifted me out of years of depression, however, I know that those experiences are mine and, one way or another, the product of activity in the brain.
Once you start taking you personal beliefs and imposing them on others, especially if you are denying the validity of the scientific method, you're straying into somewhat dangerous territory. It's certainly territory where people won't take you as seriously.
Blessings
~ND