Missed the part about the bipolar disorder...
Look I had a bipolar person who had been hospitalized for mania that wanted to take mushrooms. I thought, "hey a low dose couldn't be a big deal". I ended up not giving them too them. I'm glad I didn't. The responsibility of sending this person to a mental hospital for weeks, the legal rap that can follow that, as well as just damaging the person further, out weighs the possible good outcomes.
You see bipolar people have been taking psychedelics and some find benefits in it. However, these are mostly acute bipolars. There are two main groups bipolar people are categorized in too, referred to as '1' and '2'. The people who do dose are usually bipolar 2, and they usually take them during depressive stages so as to have a cushion for becoming manic. I can NEVER recommend dosing a bipolar person.
As a person who has a schizophreniform disorder who has taken psychedelics while psychotic, it's not really good. In general though, it wasn't that bad. Yea the whole "spice heals this" or "DMT fixes everything" may seem to be true but there are many cases where taking ANY psychedelic is not advised, and where... people aren't magically healed from years of mental illness even after many uses of psychedelics in good environments, right intentions, the whole deal. Myself and a whole slew of people I talk to on mental health boards as well. It's actually pretty cool how many people used to and do still trip on mental health forums, at least in that I fit right in.
Mania is in general more dangerous for the experiencer and those around them then psychosis is(mania can be coupled with psychosis as well). Truly manic persons can rapidly form delusions, feel invincible, be seriously agressive. Smash cars, hurt people, without any forethought nor afterthought. It can even feel like a religious experience to do such according to more than one person I've met... Essentially do things they'd never do while base-line, become hyper-sexual(sleep with tons of strangers, cheat on spouses), run straight into ridiculous amounts of debt(spend lots of cash they don't have). I've heard about it happening on mental health forums I visit, as well as on here... Psychedelics are known to induce mania in bipolars and can further exacerbate the illness is the bottom line.
You know how sometimes you get that "I'm the chosen one" on psychedelics? Manic persons often live that for days on end without any substance fueling it. Be careful when manic people ask you for things like drugs, it can often be a reckless abandon. I've read people say that each manic episode takes something from you, you can never get back. I slept with this person who wanted the mushrooms, before I knew they were bipolar and honestly that has left me feeling guilty enough. Not being able to recognize that she was hypersexual, so I educated myself a bit about the disorder.
In short, wait until the guy stabilizes and can get off of the pharmacueticals. They could be on more than bupropion, he could also be taking an antipsychotic(a lot of bipolars and schizoeffectives are). Then if he feels like risking it, make sure it's his decision for both of your sakes.
I'm not saying that this person will guaranteed lose their way, but it's a possibility that must be addressed when weighing this decision.
