DCM

[Ananda]

I'm not finding much about dichloromethane (methylene chloride) being used in extractions. What's the scoop? I've heard it's great for extracting DMT, but found nothing on anyone using it, specifically. Any links would be much appreciated!
Thanks

 

[gory dkalz]

I personally would love to try DCM in an extraction but lab grade is pretty pricey and the cheap hardware store stuff has additives and must be distilled to work. And i dont have the cash for a distilling setup. But there are some threads that cover it. I know benzyme swears by it.

P.S. sorry I can't post a link, I'm on my phone.

 

[endlessness]

Many people use it because it dissolves alkaloids really well, and it sinks to the bottom instead of staying at the top like naphtha/limonene/etc do, so its perfect for people using separatory funnels.

It might pull a lot of plant impurities too so to get crystals you would probaby have to clean it up further afterwards, but your yield would probably be very high.

The only issue is, DCM reacts with DMT after standing for some hours/days according to a couple of publications that have been posted in this forum already (I can look for it if youre interested), and it will form some chlorinated compound of unknown activity/toxicity, so be sure to evap or salt your DCM as soon as possible (within the first hour, ideally) to prevent that from happening.

 

[gory dkalz]

Would FASW be the only to salt DCM?

 

[endlessness]

Maybe FASA works fine, but I havent heard of anybody testing it. If you test it, do so with a small amount of your alkaloid-filled DCM first.. Also trying to add some FASA to pure DCM to see if fumaric acid crashes out even without alkaloids would be a good first test to make.

(edit: dont remove your question, this way if someone has the same question in the future, they can learn from what you asked)

 

[gory dkalz]

I originally asked that question thinking almost everything is miscible with DCM except water. Had a brain fart and forgot you can crash out alk's instead of using seperation. (FASA in limo vs. FASW in limo)

 

[Ananda]

I've seen the papers on pubmed about dcm reacting with dmt. Thanks tho. I'm trying to find a tek which specifically calls for dcm as the NP

 

[benzyme]

You won't find it in "teks", but you will find it used in many extraction procedures;
reactions with chlorines in DCM are not spontaneous, they require long-term exposure under basic conditions and heat.

 

[Ananda]

benzyme, would HCl, NaOH, and Dcm be suited, with use of an aspirator and funnel to further clean be acceptable? Do you have any old posts about using dcm? Appreciate it

 

[endlessness]

Benz, I have to correct you, the publications show that this reaction occurs at room temperature and there's no need for basic conditions, when DMT is dissolved in DCM after having been separated from basic solution, if it sits for 0.5-4 weeks in a closed container, the reaction happens. So even just a couple of days is enough for reaction to happen. I attached the publication here:

Scientific Articles on DMT/Ayahuasca/Psychedelics - DMT Discussion - Welcome to the DMT-Nexus

 

[benzyme]

Ok, but still not spontaneous. Who lets their extraction sit in DCM for a month anyway?
Mass spec analysis of my own DCM extractions did not show the presence of N-chloro-tryptamine derivatives

 

[benzyme]

benzyme, would HCl, NaOH, and Dcm be suited, with use of an aspirator and funnel to further clean be acceptable? Do you have any old posts about using dcm? Appreciate it

sorry, I haven't posted my mischief, but I will tell you that DCM has a high vapor pressure
so it easily evaporates. DCM is definitely my solvent of choice

 

[Ananda]

Well every place I've tried to order dcm from has denied me :/ it might just be out of the question

 

[gory dkalz]

You can get KS-3 from a hardware store and distill it.

 

[benzyme]

A certain popular auction site has it by the liter. I use DCM at 1/10th the volume of the basic solution. That's the other great thing... you can use much less DCM than naphtha in extractions

 

[Ananda]

Distilling Ks-3 won't leave behind any harmful traces, will it? If not, it seems very cost effective, considering one who would have a distillation setup readily available, of course.

 

[Mindlusion]

DCM is my choice solvent as well, It has so many wonderful qualities.

I get most of my DCM how gory dkalz mentioned, via distillation from a hardware store product.

.

About the N-chloro-DMT, my take on this reaction, is there is no issue due to its equilibrium .

I'm guessing this reaction reaches equilibrium at the same point it starts. Meaning the compound is formed, but as soon as it forms, within nanoseconds it forms the original reactants.

~
~

Im wondering if you were to put this through a mass spec, the DMT in DCM solution, and get readable results, then see if this compound is noticed in the spectrum.

 

[gory dkalz]

Is a glass distillation setup 100% required? I was thinking of using a moonshine style rig with some copper tubing but I think I read somewhere that the DCM would react with the copper.

I need it to be Christmas again so I can convince my wife I deserve glass distillation and sep funnel equipment. :lol:

 

[benzyme]

tell her you'll steam distill some essential oils to make a perfume that you'll name after her.

I had to beg my wife to let me buy a rotary evaporator, which is several hundred more than a distillation app.

*edit* btw..the ideal glass for distilling low-boiling solvents is a Dean Stark trap with a Dewar dry-ice (in acetone) condenser.

 

[Ananda]

For clarification- when distilling dcm from Ks-3 will leave me with only dcm, seeing as how the only two other ingredients (white spirits an methanol) have a much higher and somewhat higher boiling point, respectively. I won't have any trace unfriendlies condense with the dcm? If correct, my questions have been answered! Thank you Nexus!