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Effects of solvent on DMT
- Thread starter blueskine
- Start date
- Merits
- 112
Yes different dmt forms (whether its freebase or some or other salt form like fumarate, etc) will have different solubilities in different solvents
Read this, maybe it helps you understand
Also check the dmt chemical information in the wiki:
wiki.dmt-nexus.me
Read this, maybe it helps you understand
Also check the dmt chemical information in the wiki:
Psychedelic Compounds Chemical and Physical Properties - DMT-Nexus Wiki
blueshaman
Shamballa Eskatari Blu
- Merits
- 42
A better way to explain this , Is that DMT when converted to freebase form after the soaking/extraction stage, Is soluble only in a polar solvent,Such as water or Methylated spirits (ethanol 95%,Methanol 02.50% , Water 02.50%).And there are many more so technically it is soluble in any polar solvent(water is classified a solvent in chemistry terms) .
Once converted to The hydrochloride salt form ( HCL ) it changes molecular structure and becomes insoluble in polar solvents and becomes soluble in a non polar solvent such as 100% isopropyl alcohol, Toluene ( methyl-Benzene ) Any solvent that is 100% hydrocarbons such as the famed naptha (liquid form lighter fluid ) Turpentine is 100% hydrocarbons and a aromatic solvent as well but contains lubricants so is not practical to use because of the impurities. Toluene is a aromatic solvent which means that its just very strong smelling when using it in reactions. There are many solutions available that contain hydrocarbon/solvent mixtures,
Always be careful what they contain before using,And research the chemical compounds to know if they are polar or non polar. Recently i have been using a 200ml mixture of toluene and 100 hydrocarbons, It is used in arts and crafts for cleaning glue and other things. it contains 300mls toluene per litre and 700mls 100% hydrocarbons,And both are non polar with the bonus of toluene being a better non polar solvent to use.
Ive spent many hours arguing with some guys in the chemistry business about polarity being of great importance when understanding reactions and calculating which compounds to use in certain stages of synthesis, They argue that knowing the PH system and how it is used and how to test PH levels and gauge the stages of reactions by what the PH is and all that business is superior than focusing on polarity when performing reactions,
i argued that just knowing what polarity of the solvents you have on hand or are using is enough to perform basic extractions and conversions of freebase's to one of the many Hydrochloride (HCL,furmate, etc) salt forms. Pretty much we are arguing semantics and are both correct, Both the polarity and PH are important factors to know when performing any reaction or synthesis.
But i started of just focusing on learning what polarity my solvents where,So i knew which to use at different stages of my reactions. And i progressed much since then and have gained much knowledge about the PH system and to test the PH of my solutions at each point in my reactions before i add anything to progress in the synthesis.
The summary pretty much is learn about polarity of solvents before doing any reactions,This is important because a polar solvent is needed for the first step (soaking your DMT alkaloid source IE bark etc ) because the alkaloids are only soluble in polar solvents, as i mentioned above the best are methylated spirits and water. For the next stage of the reaction process you will be adding water and naoh to basify the filtered extract solution and combining them,And the way i do it is i convert straight to hydrochloride salt form (HCL) after extracting the alkaloids and converting into freebase form in the previous step,
In the next step i use a non polar solvent 100% isopropyl alcohol(often using 2, adding a aromatic non polar solvent into my pure non polar one) which is necessary to allow the DMT hcl molecules to move out of the polar layer into the non polar, In my experience this initiates the reaction but i could be wrong here as Ive observed varying results but always succeeded in obtained DMT in the end none the less. Keep in mind that i haven't explained all the necessary steps above needed to achieve success, The things i left out that you MUST separate your water layer on the bottom after basifying regardless if you intend converting to HCL form or sticking with freebase.
The reason here is that it will add impurities in you final compound,Sodium hydroxide is not a compound to take lightly, it will strip your lungs of all good/bad bacteria and eat away at your aviola sacks in your lungs and they are needed to take oxygen into your blood. Testing PH level to confirm the PH 13 when basifying,Testing PH levels after separating the basified water after basifying ( should be slightly alkaline still before washing ie PH 11,10,09,the optimum is PH 7 the same as human blood,But solvents will confuse the results so testing here always shows inaccurate results ) The trick is washing the just separated basified polar solvent solution buy adding 1/3rd the amount of water solution,Separating the bottom layer which is water,Then repeating the step by removing the water each time after the layers separate,
And adding more,Eventually the layer will become clearer and clearer until its translucent and clear,The coloring ( brown,red,yellow ) is impurities like the brown is sodium hydroxide,the yellow is impurities from the bark. Optimally you want to have the cleanest solution possible before converting to HCL if you choose to take that route. Using 100% pure solvents is a good way to be for achieving less impurities.
Once converted to The hydrochloride salt form ( HCL ) it changes molecular structure and becomes insoluble in polar solvents and becomes soluble in a non polar solvent such as 100% isopropyl alcohol, Toluene ( methyl-Benzene ) Any solvent that is 100% hydrocarbons such as the famed naptha (liquid form lighter fluid ) Turpentine is 100% hydrocarbons and a aromatic solvent as well but contains lubricants so is not practical to use because of the impurities. Toluene is a aromatic solvent which means that its just very strong smelling when using it in reactions. There are many solutions available that contain hydrocarbon/solvent mixtures,
Always be careful what they contain before using,And research the chemical compounds to know if they are polar or non polar. Recently i have been using a 200ml mixture of toluene and 100 hydrocarbons, It is used in arts and crafts for cleaning glue and other things. it contains 300mls toluene per litre and 700mls 100% hydrocarbons,And both are non polar with the bonus of toluene being a better non polar solvent to use.
Ive spent many hours arguing with some guys in the chemistry business about polarity being of great importance when understanding reactions and calculating which compounds to use in certain stages of synthesis, They argue that knowing the PH system and how it is used and how to test PH levels and gauge the stages of reactions by what the PH is and all that business is superior than focusing on polarity when performing reactions,
i argued that just knowing what polarity of the solvents you have on hand or are using is enough to perform basic extractions and conversions of freebase's to one of the many Hydrochloride (HCL,furmate, etc) salt forms. Pretty much we are arguing semantics and are both correct, Both the polarity and PH are important factors to know when performing any reaction or synthesis.
But i started of just focusing on learning what polarity my solvents where,So i knew which to use at different stages of my reactions. And i progressed much since then and have gained much knowledge about the PH system and to test the PH of my solutions at each point in my reactions before i add anything to progress in the synthesis.
The summary pretty much is learn about polarity of solvents before doing any reactions,This is important because a polar solvent is needed for the first step (soaking your DMT alkaloid source IE bark etc ) because the alkaloids are only soluble in polar solvents, as i mentioned above the best are methylated spirits and water. For the next stage of the reaction process you will be adding water and naoh to basify the filtered extract solution and combining them,And the way i do it is i convert straight to hydrochloride salt form (HCL) after extracting the alkaloids and converting into freebase form in the previous step,
In the next step i use a non polar solvent 100% isopropyl alcohol(often using 2, adding a aromatic non polar solvent into my pure non polar one) which is necessary to allow the DMT hcl molecules to move out of the polar layer into the non polar, In my experience this initiates the reaction but i could be wrong here as Ive observed varying results but always succeeded in obtained DMT in the end none the less. Keep in mind that i haven't explained all the necessary steps above needed to achieve success, The things i left out that you MUST separate your water layer on the bottom after basifying regardless if you intend converting to HCL form or sticking with freebase.
The reason here is that it will add impurities in you final compound,Sodium hydroxide is not a compound to take lightly, it will strip your lungs of all good/bad bacteria and eat away at your aviola sacks in your lungs and they are needed to take oxygen into your blood. Testing PH level to confirm the PH 13 when basifying,Testing PH levels after separating the basified water after basifying ( should be slightly alkaline still before washing ie PH 11,10,09,the optimum is PH 7 the same as human blood,But solvents will confuse the results so testing here always shows inaccurate results ) The trick is washing the just separated basified polar solvent solution buy adding 1/3rd the amount of water solution,Separating the bottom layer which is water,Then repeating the step by removing the water each time after the layers separate,
And adding more,Eventually the layer will become clearer and clearer until its translucent and clear,The coloring ( brown,red,yellow ) is impurities like the brown is sodium hydroxide,the yellow is impurities from the bark. Optimally you want to have the cleanest solution possible before converting to HCL if you choose to take that route. Using 100% pure solvents is a good way to be for achieving less impurities.
