DMT tends to stop effecting me. I can blow thru 100mg with little more than slight OEV and CEV typically nonexistent. I’ve even tried sublingual harmalas during these times and the effects stay quite weak. I guess my mind is adept at defending against the dmt. Perhaps some receptors have down regulated. Anyway I’m curious how many other people have similar experiences. How long of a break was necessary to get full effects again? Any other changes that made a difference? Would taking harmalas alone for some time period help?