I could certainly see it as possible, albeit undesirable, imo. Given the reverse tolerance of harmala alkaloids taken over extended durations, it's even plausible that you could use less and less and wind up in the same spaces. The issues would be psychological and dietary, imo. Such a long-term inhibition of MAO, even with a RIMA would probably necessitate maintaining a more traditional ayahuasca diet and who knows how you would feel emotionally/mentally in the wake of such a doozy. I imagine integration would be rather arduous.