GF has same thing, sometimes 3 days in bed with the migraine. I feel for you!
She also saw a neurologist and he blamed genes, period.
She did the typical routine, brain encephalogram,...
But even with those genes the neurologists can't explain why it hits and vanishes without a further clue. They can point to some triggers but not calling them real sources.
She also had triptanes, Imitrex. (same as sumatriptan)
Yes expensive.
The neurologists have to scan a variety of products to see what works best for a person, real try and error stuff, no choice.
He also made a subscription for suppository pain killer to be made by the pharmacist by recipe. These were actually cheap to buy and helpful when taken in the onset to block the migraine rise. The recipe is:
Indomethacine 75mg
Amylocaine Hcl 25mg
Coffeine (water free) 50 mg
Witepsol E85 Ad 2gr <--- the white suppository matter IIRC
On page 5 of 16 you can find pretty same recipe in the chart diagram:
Here the doses are even higher.
About Indomethacine:
If I'm not mistaken this recipe is in 1 suppository.
This was her best weapon lesser than the Imitrex.
They were always cheap and suddenly more expensive and we asked the pharmacist why. He replied that this was only due the kind of coffeine used and that he could easily trade for another type of coffeine that was still cheap. IIRC that was a difference between water free or not. I have no recall which one went more expensive.
Maybe you can propose such recipe to a doctor? Or a variation on it?
She preferred suppository because she never could hold anything in the stomach during such an episode, the nausea you know.
Man I really hope you find something to help you.
Non psychedelic triptamines somehow?
www.webmd.com

She also saw a neurologist and he blamed genes, period.
She did the typical routine, brain encephalogram,...
But even with those genes the neurologists can't explain why it hits and vanishes without a further clue. They can point to some triggers but not calling them real sources.
She also had triptanes, Imitrex. (same as sumatriptan)
Yes expensive.
The neurologists have to scan a variety of products to see what works best for a person, real try and error stuff, no choice.
He also made a subscription for suppository pain killer to be made by the pharmacist by recipe. These were actually cheap to buy and helpful when taken in the onset to block the migraine rise. The recipe is:
Indomethacine 75mg
Amylocaine Hcl 25mg
Coffeine (water free) 50 mg
Witepsol E85 Ad 2gr <--- the white suppository matter IIRC
On page 5 of 16 you can find pretty same recipe in the chart diagram:
Here the doses are even higher.
About Indomethacine:
https://headaches.org/2007/10/25/indocin-indomethacin/ said:...Some headaches such as episodic and chronic paroxysmal hemicrania are exclusively responsive to indomethacin. It is the medication of first choice in these types of headache. Indomethacin may also be helpful in headache related to physical stress or exertional headache. It has been shown to be effective in migraine both for prevention of migraine as well as treating the acute migraine attack.
Indomethacin is available in immediate or sustained-release (SR) pill form and can be compounded by certain pharmacies as a rectal suppository.
Tags: acute migraine attack, analgesic, anti-inflammatory drug, diarrhea, exertional headache, headache, indocin, indomethacin, NSAIDs, side effects
...
If I'm not mistaken this recipe is in 1 suppository.
This was her best weapon lesser than the Imitrex.
They were always cheap and suddenly more expensive and we asked the pharmacist why. He replied that this was only due the kind of coffeine used and that he could easily trade for another type of coffeine that was still cheap. IIRC that was a difference between water free or not. I have no recall which one went more expensive.
Maybe you can propose such recipe to a doctor? Or a variation on it?
She preferred suppository because she never could hold anything in the stomach during such an episode, the nausea you know.
Man I really hope you find something to help you.
Non psychedelic triptamines somehow?
Triptans (Serotonin Receptor Agonists) for Migraine Headaches
These drugs can stop migraines after they start, but WebMD explains why they're not the right fit for everyone who gets a migraine.


