I’ve found that having blends that are harmala heavy are more meditative and medicinal on a somatic level, while DMT heavy blends are more like… DMT and have the benefit of being more in line with a typical psychedelic experience, just lengthened and softened by the harmalas and a reset to the default mode network. Now, these observations are dependant on dose, of course.
Harmala heavy blends may cause more instances of purging, not unlike with Aya.
If I had to give a minimum amount of harmalas to suggest, I’d say no less than 200mg per gram of DMT.