NDRI and MAOI

[Trev_sunyata]

It's ok to take MAOIs with NDRIs right?
This one's related to phenylethylamines.
Are there any drugs that interact badly with NDRIs?

Side question I thought of while typing:
Would an MAOI be a good idea to take before ingesting LSA extract?

 

[Sabnock1990]

It's the Serotonin and Noradrenaline you gotta be concerned about, Dopamine not so much as MAO-A inhibition doesn't seem all that Dopaminergic ime. I've taken some Isopropylphenidate with Moclobemide a couple times and didn't notice really any issues, also have taken Mucuna/L-Dopa with Moclobemide, as well as Harmalas/Rue, seems to work fine, but too much Noradrenaline could cause a hypertensive crisis or increased heart rate and such, not inherently dangerous, but could be problematic with a high enough dosage imo, i'd say give Mucuna a try, works nicely, been taking it twice a day everyday for a year and a month now.

 

[dreamer042]

Harmalas have fairly significant nor-epinephrine activity, such a combination is contraindicated. As a general rule of thumb it's typically not a good idea to mix any reuptake inhibitor with a RIMA/MAOI.