karloff
Rising Star
After my success with DMT and harmalas extractions, and failure with bufotenine, I have tried extracting LSA from HBWR this week. This is a summary of the procedure I followed:
-Grind 10 gr. of HBWR to powder.
-Defat 4x with heptane. The solvent was mixed for hours in a magnetic stirrer and then some more hours to settle.
-After defat, dry the plant material and extract 3x with lab grade methanol. Also used magnetic stirrer to mix for hours.
-Finally, once methanol was evaporated, I obtained 1.1 gr. of brownish crystals:
This is like 10% yield, while the published alkaloid contents of HBWR is about 0.3%, so my final product is still very impure.
I am not sure what to do now for purifying this extract as much as possible. I am thinking about freebasing it and then make some fumarate salts, but the info I am gathering is a bit confusing, despite how much I am searching in this and other sites. I suspect this stuff does not work like with dmt extractions, so I don't feel very confident.
Please if somebody can help with some ideas, I would be very thankful.
These are the products I can dispose for the next steps:
-NP solvents: heptane, limonene.
-Polar solvents: water, methanol, ethanol, IPA, MEK.
-Acids: citric, tartaric, fumaric, acetic.
-Bases: NAOH, Sodium carbonate, KOH, ammonia.
Any ideas? Thank you very much in advance.
-Grind 10 gr. of HBWR to powder.
-Defat 4x with heptane. The solvent was mixed for hours in a magnetic stirrer and then some more hours to settle.
-After defat, dry the plant material and extract 3x with lab grade methanol. Also used magnetic stirrer to mix for hours.
-Finally, once methanol was evaporated, I obtained 1.1 gr. of brownish crystals:

This is like 10% yield, while the published alkaloid contents of HBWR is about 0.3%, so my final product is still very impure.
I am not sure what to do now for purifying this extract as much as possible. I am thinking about freebasing it and then make some fumarate salts, but the info I am gathering is a bit confusing, despite how much I am searching in this and other sites. I suspect this stuff does not work like with dmt extractions, so I don't feel very confident.
Please if somebody can help with some ideas, I would be very thankful.
These are the products I can dispose for the next steps:
-NP solvents: heptane, limonene.
-Polar solvents: water, methanol, ethanol, IPA, MEK.
-Acids: citric, tartaric, fumaric, acetic.
-Bases: NAOH, Sodium carbonate, KOH, ammonia.
Any ideas? Thank you very much in advance.