I think Evening Glorys post is your best answer here.
The potential for brain tumours to cause seizures depends on a number of known (and almost certainly, some unknown) factors.
These include:
1.Is it a primary brain tumour or a cerebral metastasis?If metastatic ie spread to the brain from another site, whats the nature of the primary tumour?
2.Whats its location ie cortical/subcortical or indeed elsewhere?
3.Its size and whether or not its compressing surrounding tissues ie causing mass effect?
4.Whats its histology?
5.Is it causing secondary electrolyte abnormalities such as hyponatremia (for example low plasma sodium through inappropriate Anti Diuretic Hormone release)?
6.Is the patient on any medications for any purpose which can alter the seizure threshold? This includes fairly commonly used medications such as ibuprofen,penicillins and ciprofloxacin.
Do bear in mind that our understanding of much of the central nervous system, its correct functioning and indeed its behaviour in disease is pretty crude;its also the case that one persons ailments will not always follow a set textbook pattern.
Psilocybin has been shown to cause seizures in children who have taken it inadvertently;this may simply reflect the fact that the immature brain responds in a different fashion to that of adults but it cannot be stated conclusively that the brain when suffering a disease process will behave exactly the same as an undiseased brain when exposed to exogenous substances.
I may be wrong here but hasnt 5 meo-DMT been responsible for seizures,admittedly when taken beyond the standard dose range?
Im sure a neurologist would advise against taking something the effects of which cannot be predicted with any firm degree of accuracy.This is (in part) to cover their ass so theres no Tribunal/Hearing assessing their fitness to practise somewhere down the line but also to live up to the spirit of the Hippocratic Oath (ie do no harm).But whether or not it would cause a problem in any particular patient, I dont think anyone can say for sure.
But there are potentially bigger problems than a seizure to bear in mind.For example, certain secondary tumours in the brain (such as metastatic malignant melanoma) are highly vascular but the vessels wall are weak and prone to spontaneously rupture (known as apoplexy)-this can occur for no observable reason or as a consequence of fits resulting in all the problems which can come from a cerebral hemorrhage.
Sorry for the grim nature of this post but I do love neurology!!!!
