By RoLFBERGIN, DIEGO CARLSTR6M, GORAN FALKENBERG and HANS RINGERTZ
Department of Medical Physics, Karolinska Institutet, Stockholm 60,Sweden(Received 13 February 1968)
Department of Medical Physics, Karolinska Institutet, Stockholm 60,Sweden(Received 13 February 1968)
Crystallographic data are given for the N,N-dimethyl, 5-hydroxy-N,N-dimethyl, 5-methoxy-N,N-dimethyland 5-methoxy-N-methyl derivatives of tryptamine. As part of a crystallographic investigation of substances affecting the central nervous system, some psychoactive indole bases have been studied: N,N-dimethyltryptamine(DMT), 5-hydroxy-N,N-dimethyltryptamine (5-OH-DMTor bufotenine), 5-methoxy-N,N-dimethyltryptamine (5-MeO-DMT) and 5-methoxy-N-monomethyltryptamine (5-MeO-MMT).The X-ray data were obtained from oscillation and Weissenberg photographs with Cu K~ radiation, except for DMT, the constants of which were determined with an automatic diffractometer, PAILRED, using Mo K~ radiation. The determinations of density were made by flotation in Clerici solution. The melting-points were measured in a Leitz hot-stage microscope. Our thanks are due to Professor B. Holmstedt, Department of Toxicology, Karolinska Instituter, for supplying us with material. The work was supported by the Swedish Medical Research Council (Project No. B 68-11 X-144-04 B).